Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.51 |
| ▸ | GAA | P10253 | 9/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.51 |
| ▸ | HPGD | P15428 | 8/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.51 |
| ▸ | NOTUM | Q6P988 | 5/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | GLA | P06280 | 4/20 | 0.47 |
| ▸ | HTT | P42858 | 4/20 | 0.47 |
| ▸ | CASP1 | P29466 | 3/20 | 0.47 |
| ▸ | CASP7 | P55210 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | STAT3 | P40763 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16368697 | 0.88 | NOTUM (0.53) | NOTUMPIK3CA | |
| SCHEMBL16368693 | 0.79 | KDM4E (0.47) | ALDH1A1GAAKDM4EHPGDNOTUM | |
| SCHEMBL15173555 | 0.78 | KDM4E (0.63) | ALDH1A1GAAKDM4EHPGDHSD17B10 | |
| SCHEMBL15172972 | 0.78 | ALDH1A1 (0.51) | ALDH1A1GAAKDM4EHPGDHSD17B10 | |
| SCHEMBL15173197 | 0.72 | ALDH1A1 (0.62) | ALDH1A1GAAKDM4EHPGDHSD17B10 | |
| SCHEMBL15188504 | 0.71 | RAB9A (0.42) | ALDH1A1KDM4EHPGDMAPK1MAPT | |
| SCHEMBL15188517 | 0.71 | NPC1 (0.45) | ALDH1A1HPGDTP53SMN1; SMN2TSHR | |
| SCHEMBL20597636 | 0.70 | NOTUM (0.81) | ALDH1A1GAAKDM4EHPGDHSD17B10 | |
| SCHEMBL20597657 | 0.70 | NOTUM (0.81) | ALDH1A1GAAKDM4EHPGDHSD17B10 | |
| SCHEMBL20597360 | 0.69 | NOTUM (0.63) | ALDH1A1GAAKDM4EHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9073942-B2 | Antiviral compounds with a heterotricycle moiety | LUPIN LIMITED (IN) | 2015-07-07 | — | — | US | disclosed |
| US-20150010504-A1 | Antiviral Compounds with a Heterotricycle Moiety | LUPIN LIMITED (IN) | 2015-01-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150010504-A1 | Antiviral Compounds with a Heterotricycle Moiety | HCCS, UQCRB, HAVCR2 | ALDH1A1 2083/4885GAA 1402/4885KDM4E 3535/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.