Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 3/20 | 0.33 |
| ▸ | PDE5A | O76074 | 11/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16370404 | 0.86 | DGAT1 (0.39) | DGAT1PDE5A | |
| SCHEMBL16370484 | 0.78 | DGAT1 (0.39) | DGAT1PDE5A | |
| SCHEMBL17766175 | 0.77 | PDE5A (0.38) | DGAT1PDE5A | |
| SCHEMBL18671464 | 0.75 | PDE5A (0.32) | PDE5A | |
| SCHEMBL16370332 | 0.72 | PDE5A (0.38) | DGAT1PDE5A | |
| SCHEMBL16370265 | 0.71 | PDE5A (0.63) | PDE5A | |
| SCHEMBL16370351 | 0.70 | PDE5A (0.62) | PDE5A | |
| SCHEMBL18671467 | 0.68 | PDE5A (0.33) | PDE5A | |
| Acetic Acid SCHEMBL17766178 | 0.67 | NPC1 (0.36) | DGAT1 | |
| SCHEMBL16370085 | 0.67 | DGAT1 (0.33) | DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3019506-A1 | BENZYL-1H-PYRAZOLO[3,4-B]PYRIDINES AND USE THEREOF | Bayer Pharma Aktiengesellschaft (DE) | 2016-05-18 | — | — | EP | disclosed |
| WO-2015004105-A1 | BENZYL-1H-PYRAZOLO[3,4-B]PYRIDINES AND USE THEREOF | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2015-01-15 | — | — | WO | disclosed |