Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 11/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18671464 | 0.91 | PDE5A (0.32) | PDE5A | |
| SCHEMBL16370484 | 0.89 | DGAT1 (0.39) | PDE5A | |
| SCHEMBL16370404 | 0.80 | DGAT1 (0.39) | PDE5A | |
| SCHEMBL16370368 | 0.77 | PDE5A (0.54) | PDE5A | |
| SCHEMBL18671456 | 0.77 | PDE5A (0.37) | PDE5A | |
| SCHEMBL18671465 | 0.71 | PDE5A (0.62) | PDE5A | |
| SCHEMBL16370287 | 0.68 | PDE5A (0.55) | PDE5A | |
| SCHEMBL16370565 | 0.68 | PDE5A (0.45) | PDE5A | |
| SCHEMBL16370405 | 0.68 | DGAT1 (0.33) | PDE5A | |
| SCHEMBL18671460 | 0.68 | ADORA1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9605008-B2 | Benzyl-1H-pyrazolo[3,4-b]pyridines and use thereof | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2017-03-28 | — | — | US | disclosed |