Sugi Predict

Sugi Predict / Compounds / SCHEMBL16370925

SCHEMBL16370925

SCHEMBL16370925

OBO.c1ccc2c3ccc-3c2c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ IDO1 P14902 2/20 0.42
▸ ALDH1A1 P00352 5/20 0.37
▸ HSD17B10 Q99714 3/20 0.37
▸ TDP1 Q9NUW8 3/20 0.37
▸ CYP2A6 P11509 2/20 0.37
▸ TSHR P16473 1/20 0.37
▸ CYP1A2 P05177 3/20 0.35
▸ CRHBP P24387 1/20 0.35
▸ CRHR2 Q13324 1/20 0.35
▸ KEAP1 Q14145 1/20 0.35
▸ NFE2L2 Q16236 1/20 0.35
▸ KDM4E B2RXH2 5/20 0.33
▸ GPR3 P46089 3/20 0.33
▸ MAPT P10636 2/20 0.33
▸ SMN1; SMN2 Q16637 2/20 0.33
▸ CA12 O43570 2/20 0.33
▸ CA2 P00918 2/20 0.33
▸ CA3 P07451 2/20 0.33
▸ CA4 P22748 2/20 0.33
▸ CA14 Q9ULX7 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Triphenylene SCHEMBL23151828 0.85 IDO1 (0.47) IDO1ALDH1A1HSD17B10TDP1CYP2A6
Ammonia Solution, Strong SCHEMBL3586937 0.81 ALDH1A1 (0.44) IDO1ALDH1A1HSD17B10TDP1CYP2A6
Naphthalene SCHEMBL2270334 0.74 CYP2A6 (0.61) ALDH1A1HSD17B10TDP1CYP2A6TSHR
SCHEMBL442916 0.73 IDO1 (0.81) IDO1ALDH1A1HSD17B10TDP1TSHR
Sulfuric Acid SCHEMBL391429 0.73 SMN1; SMN2 (0.46) IDO1ALDH1A1HSD17B10TDP1TSHR
Phenanthrene SCHEMBL15911090 0.73 HSD17B10 (0.75) ALDH1A1HSD17B10TDP1CYP2A6TSHR
SCHEMBL13265824 0.73 IDO1 (0.81) IDO1ALDH1A1HSD17B10TDP1TSHR
Naphthalene SCHEMBL215802 0.69 CYP2A6 (0.67) ALDH1A1HSD17B10TDP1CYP2A6TSHR
Carbazole SCHEMBL1930530 0.69 ALDH1A1 (0.78) IDO1ALDH1A1HSD17B10CYP1A2KDM4E
Dibenzothiophene SCHEMBL911430 0.69 GPR3 (0.78) ALDH1A1TDP1CYP1A2KDM4EGPR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10770663-B2 Germanium-centered dendrimer compound, and organic optoelectric element comprising same CHUNG-ANG UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) 2020-09-08 — — US disclosed
US-20160141520-A1 GERMANIUM-CENTERED DENDRIMER COMPOUND, AND ORGANIC OPTOELECTRIC ELEMENT COMPRISING SAME CHUNG-ANG UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) 2016-05-19 — — US disclosed
WO-2015005680-A1 GERMANIUM-CENTERED DENDRIMER COMPOUND, AND ORGANIC OPTOELECTRIC ELEMENT COMPRISING SAME 중앙대학교 산학협력단 (KR) 2015-01-15 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10770663-B2 Germanium-centered dendrimer compound, and organic optoelectric element comprising same GRK1, OCIAD2, CD40LG IDO1 4498/4885ALDH1A1 2175/4885HSD17B10 4208/4885
US-20160141520-A1 GERMANIUM-CENTERED DENDRIMER COMPOUND, AND ORGANIC OPTOELECTRIC ELEMENT COMPRISING SAME GRK1, OCIAD2, CD40LG IDO1 4498/4885ALDH1A1 2175/4885HSD17B10 4208/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.