Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 4/20 | 0.55 |
| ▸ | TAS1R1 | Q7RTX1 | 4/20 | 0.55 |
| ▸ | TAS1R2 | Q8TE23 | 4/20 | 0.55 |
| ▸ | FPR1 | P21462 | 5/20 | 0.43 |
| ▸ | FPR2 | P25090 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | AKT1 | P31749 | 4/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17799742 | 1.00 | TAS1R3 (0.55) | TAS1R3TAS1R1TAS1R2FPR1FPR2 | |
| SCHEMBL16372251 | 0.91 | GAA (0.55) | TAS1R3TAS1R1TAS1R2GAAHCRTR1 | |
| SCHEMBL17799682 | 0.91 | GAA (0.55) | TAS1R3TAS1R1TAS1R2GAAHCRTR1 | |
| SCHEMBL15291806 | 0.86 | L3MBTL1 (0.46) | TAS1R3TAS1R1TAS1R2FPR1FPR2 | |
| SCHEMBL16392343 | 0.86 | L3MBTL1 (0.46) | TAS1R3TAS1R1TAS1R2FPR1FPR2 | |
| SCHEMBL15294774 | 0.86 | L3MBTL1 (0.46) | TAS1R3TAS1R1TAS1R2FPR1FPR2 | |
| SCHEMBL17799705 | 0.84 | NPC1 (0.47) | FPR1FPR2HCRTR1P2RX7 | |
| SCHEMBL17799764 | 0.83 | TAS1R3 (0.52) | TAS1R3TAS1R1TAS1R2GAACNR1 | |
| SCHEMBL17799667 | 0.81 | HCRTR1 (0.43) | TAS1R3TAS1R1TAS1R2FPR1FPR2 | |
| SCHEMBL16372233 | 0.81 | HCRTR1 (0.43) | TAS1R3TAS1R1TAS1R2FPR1FPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3019476-A1 | 4-MEMBERED RING CARBOXAMIDES USED AS NEMATICIDES | Syngenta Participations AG (CH) | 2016-05-18 | — | — | EP | disclosed |
| WO-2015003951-A1 | 4-MEMBERED RING CARBOXAMIDES USED AS NEMATICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2015-01-15 | — | — | WO | disclosed |