Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 4/20 | 0.52 |
| ▸ | TAS1R1 | Q7RTX1 | 4/20 | 0.52 |
| ▸ | TAS1R2 | Q8TE23 | 4/20 | 0.52 |
| ▸ | DPP4 | P27487 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PPIA | P62937 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
| ▸ | TYK2 | P29597 | 1/20 | 0.38 |
| ▸ | CDK9 | P50750 | 1/20 | 0.38 |
| ▸ | JAK3 | P52333 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16372345 | 0.91 | GAA (0.53) | TAS1R3TAS1R1TAS1R2GAAHCRTR1 | |
| SCHEMBL17799678 | 0.91 | GAA (0.53) | TAS1R3TAS1R1TAS1R2GAAHCRTR1 | |
| SCHEMBL17799725 | 0.88 | GAA (0.46) | TAS1R3TAS1R1TAS1R2DPP4GAA | |
| SCHEMBL17799743 | 0.87 | SLC6A12 (0.47) | TAS1R3TAS1R1TAS1R2HCRTR1SLC6A12 | |
| SCHEMBL16220951 | 0.85 | L3MBTL1 (0.57) | TAS1R3TAS1R1TAS1R2MEN1KMT2A | |
| SCHEMBL17799726 | 0.85 | DPP4 (0.40) | TAS1R3TAS1R1TAS1R2DPP4GAA | |
| SCHEMBL17799686 | 0.85 | DPP4 (0.40) | TAS1R3TAS1R1TAS1R2DPP4GAA | |
| SCHEMBL16372454 | 0.85 | TAS1R3 (0.39) | TAS1R3TAS1R1TAS1R2DPP4GAA | |
| SCHEMBL16372225 | 0.84 | GAA (0.41) | TAS1R3TAS1R1TAS1R2DPP4GAA | |
| SCHEMBL17799731 | 0.84 | TSHR (0.54) | GAAMEN1KMT2AL3MBTL1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE50724-E1 | 4-membered ring carboxamides used as nematicides | SYNGENTA CROP PROTECTION AG (CH) | 2026-01-06 | — | — | US | disclosed |
| EP-3019476-B1 | 4-MEMBERED RING CARBOXAMIDES USED AS NEMATICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2018-01-17 | — | — | EP | disclosed |
| US-9867371-B2 | 4-membered ring carboxamides used as nematicides | SYNGENTA PARTICIPATIONS AG (CH) | 2018-01-16 | — | — | US | disclosed |
| US-20160157485-A1 | 4-MEMBERED RING CARBOXAMIDES USED AS NEMATICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2016-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160157485-A1 | 4-MEMBERED RING CARBOXAMIDES USED AS NEMATICIDES | TUBA3C, DDT, CYCS | TAS1R3 3195/4885TAS1R1 3418/4885TAS1R2 2989/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.