Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.40 |
| ▸ | CNR1 | P21554 | 8/20 | 0.38 |
| ▸ | CNR2 | P34972 | 8/20 | 0.38 |
| ▸ | DPP4 | P27487 | 3/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.38 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17799647 | 1.00 | GRM5 (0.40) | GRM5P2RX7CNR1CNR2DPP4 | |
| SCHEMBL17799674 | 0.88 | GRM5 (0.39) | GRM5P2RX7CNR1CNR2DPP4 | |
| SCHEMBL17799639 | 0.87 | GRM5 (0.55) | GRM5P2RX7DPP4TAS1R3TAS1R1 | |
| SCHEMBL16372105 | 0.87 | GRM5 (0.55) | GRM5P2RX7DPP4TAS1R3TAS1R1 | |
| SCHEMBL17799739 | 0.86 | P2RX7 (0.38) | GRM5P2RX7CNR1CNR2DPP4 | |
| SCHEMBL16371852 | 0.85 | P2RX7 (0.44) | GRM5P2RX7DPP4ALDH1A1SMN1; SMN2 | |
| SCHEMBL17799684 | 0.85 | P2RX7 (0.44) | GRM5P2RX7DPP4ALDH1A1SMN1; SMN2 | |
| SCHEMBL19767309 | 0.85 | DPP4 (0.38) | GRM5P2RX7CNR1CNR2DPP4 | |
| SCHEMBL16372250 | 0.84 | P2RX7 (0.43) | GRM5P2RX7DPP4TAS1R3TAS1R1 | |
| SCHEMBL17799715 | 0.84 | P2RX7 (0.43) | GRM5P2RX7DPP4TAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3019476-A1 | 4-MEMBERED RING CARBOXAMIDES USED AS NEMATICIDES | Syngenta Participations AG (CH) | 2016-05-18 | — | — | EP | disclosed |
| WO-2015003951-A1 | 4-MEMBERED RING CARBOXAMIDES USED AS NEMATICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2015-01-15 | — | — | WO | disclosed |