Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 3/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 5/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.35 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 2/20 | 0.35 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19767312 | 0.92 | HCRTR1 (0.41) | DPP4P2RX7HCRTR1GRM5TAS1R3 | |
| SCHEMBL19767310 | 0.86 | TYK2 (0.41) | P2RX7HCRTR1ALDH1A1SMN1; SMN2TAS1R3 | |
| SCHEMBL17799647 | 0.85 | GRM5 (0.40) | DPP4P2RX7GRM5ALDH1A1SMN1; SMN2 | |
| SCHEMBL16371880 | 0.85 | GRM5 (0.40) | DPP4P2RX7GRM5ALDH1A1SMN1; SMN2 | |
| SCHEMBL17799674 | 0.85 | GRM5 (0.39) | DPP4P2RX7HCRTR1GRM5TAS1R3 | |
| SCHEMBL17799739 | 0.83 | P2RX7 (0.38) | DPP4P2RX7HCRTR1GRM5ALDH1A1 | |
| SCHEMBL19767307 | 0.82 | HCRTR1 (0.43) | P2RX7HCRTR1GRM5 | |
| SCHEMBL16371852 | 0.81 | P2RX7 (0.44) | DPP4P2RX7HCRTR1GRM5ALDH1A1 | |
| SCHEMBL17799684 | 0.81 | P2RX7 (0.44) | DPP4P2RX7HCRTR1GRM5ALDH1A1 | |
| SCHEMBL16372105 | 0.81 | GRM5 (0.55) | DPP4P2RX7HCRTR1GRM5ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9867371-B2 | 4-membered ring carboxamides used as nematicides | SYNGENTA PARTICIPATIONS AG (CH) | 2018-01-16 | — | — | US | disclosed |