SCHEMBL1637207

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1635446	0.96	ALOX5 (0.45)	ALOX5KDM4EATML3MBTL1PRKDC
	SCHEMBL5029698	0.91	ALOX5 (0.46)	ALOX5KDM4EATML3MBTL1PRKDC
	SCHEMBL17871071	0.90	ALOX5 (0.55)	ALOX5KDM4EATML3MBTL1PRKDC
	SCHEMBL5028208	0.90	KDM4E (0.47)	ALOX5KDM4EATML3MBTL1PRKDC
	SCHEMBL9890261	0.90	ALOX5 (0.40)	ALOX5KDM4EATML3MBTL1PRKDC
	SCHEMBL10038499	0.90	ALOX5 (0.48)	ALOX5KDM4EATML3MBTL1PRKDC
	SCHEMBL1636371	0.88	KDM4E (0.45)	ALOX5KDM4EATML3MBTL1PRKDC
	SCHEMBL16171143	0.88	ALOX5 (0.45)	ALOX5KDM4EATML3MBTL1PRKDC
	SCHEMBL21583638	0.88	ALOX5 (0.52)	ALOX5KDM4EATML3MBTL1PRKDC
	SCHEMBL21583636	0.88	ALOX5 (0.52)	ALOX5KDM4EATML3MBTL1PRKDC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.