Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.61 |
| ▸ | HPGD | P15428 | 2/20 | 0.61 |
| ▸ | GAA | P10253 | 2/20 | 0.61 |
| ▸ | HSD17B1 | P14061 | 4/20 | 0.56 |
| ▸ | HSD17B2 | P37059 | 4/20 | 0.56 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | RXRB | P28702 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | UCHL1 | P09936 | 3/20 | 0.36 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.36 |
| ▸ | KDM3B | Q7LBC6 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | KDM6B | O15054 | 1/20 | 0.36 |
| ▸ | KDM4A | O75164 | 1/20 | 0.36 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.36 |
| ▸ | HIF1AN | Q9NWT6 | 1/20 | 0.36 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22867945 | 0.85 | HSD17B1 (0.54) | KDM4EHSD17B10HPGDGAAHSD17B1 | |
| SCHEMBL17782171 | 0.82 | HSD17B1 (0.55) | KDM4EHSD17B10HPGDGAAHSD17B1 | |
| SCHEMBL22867444 | 0.79 | KDM4E (0.43) | KDM4EHSD17B10HPGDGAAHSD17B1 | |
| SCHEMBL16372100 | 0.77 | HSD17B1 (0.48) | KDM4EHSD17B1HSD17B2POLB | |
| SCHEMBL12167565 | 0.76 | KDM4E (1.00) | KDM4EHSD17B10HPGDGAANOTUM | |
| SCHEMBL16372116 | 0.76 | HSD17B1 (0.43) | KDM4EHSD17B10HPGDGAAHSD17B1 | |
| SCHEMBL22867809 | 0.72 | HSD17B2 (1.00) | HSD17B1HSD17B2 | |
| SCHEMBL1929372 | 0.72 | NOTUM (0.41) | KDM4EHSD17B10HPGDGAAHSD17B1 | |
| SCHEMBL16371314 | 0.71 | KDM4E (0.42) | KDM4EHSD17B10HPGDGAANOTUM | |
| SCHEMBL16372082 | 0.70 | HSD17B2 (0.47) | KDM4EHSD17B10HPGDGAAHSD17B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160150782-A1 | USE OF SELECTED PYRIDONE CARBOXAMIDES OR SALTS THEREOF AS ACTIVE SUBSTANCES AGAINST ABIOTIC PLANT STRESS | BAYER CROPSCIENCE AG (DE) | 2016-06-02 | — | — | US | disclosed |
| EP-3019012-A1 | USE OF SELECTED PYRIDONE CARBOXAMIDES OR SALTS THEREOF AS ACTIVE SUBSTANCES AGAINST ABIOTIC PLANT STRESS | Bayer CropScience AG (DE) | 2016-05-18 | — | — | EP | disclosed |
| CN-105530814-A | Use of selected pyridone carboxamides or salts thereof as active substances against abiotic plant stress | BAYER CROPSCIENCE AG | 2016-04-27 | — | — | CN | disclosed |
| WO-2015004040-A1 | USE OF SELECTED PYRIDONE CARBOXAMIDES OR SALTS THEREOF AS ACTIVE SUBSTANCES AGAINST ABIOTIC PLANT STRESS | BAYER CROPSCIENCE AG (DE) | 2015-01-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160150782-A1 | USE OF SELECTED PYRIDONE CARBOXAMIDES OR SALTS THEREOF AS ACTIVE SUBSTANCES AGAINST ABIOTIC PLANT STRESS | PDXK, PLPBP, PNPO | KDM4E 1838/4885HSD17B10 1548/4885HPGD 72/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.