SCHEMBL1637262

SCHEMBL1637262

Cc1ccc([N]c2ccc(C)cc2C)c(C)c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 3/20 0.54
NPC1 O15118 2/20 0.54
CYP3A4 P08684 1/20 0.54
ADRA2A P08913 1/20 0.54
TDP1 Q9NUW8 2/20 0.46
TP53 P04637 1/20 0.46
LMNA P02545 4/20 0.44
MAPT P10636 4/20 0.44
ALDH1A1 P00352 6/20 0.43
KDM4E B2RXH2 3/20 0.43
HTT P42858 2/20 0.43
GAA P10253 4/20 0.42
THRB P10828 2/20 0.42
POLB P06746 1/20 0.42
PKM P14618 1/20 0.42
HPGD P15428 1/20 0.42
ALOX15 P16050 1/20 0.42
TSHR P16473 1/20 0.42
ALOX12 P18054 1/20 0.42
MPI P34949 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11693231 0.83 NPC1 (0.72) RAB9ANPC1CYP3A4ADRA2ATDP1
SCHEMBL11693234 0.83 NPC1 (0.72) RAB9ANPC1CYP3A4ADRA2ATDP1
SCHEMBL5932966 0.82 FTO (0.46) RAB9ANPC1CYP3A4ADRA2ATDP1
SCHEMBL7050721 0.81 NPC1 (0.52) RAB9ANPC1CYP3A4ADRA2ATDP1
SCHEMBL16122112 0.79 NPC1 (0.50) RAB9ANPC1CYP3A4ADRA2ATDP1
SCHEMBL12589735 0.79 RAB9A (0.50) RAB9ANPC1CYP3A4ADRA2ATDP1
SCHEMBL15417588 0.79 NPC1 (0.50) RAB9ANPC1CYP3A4ADRA2ATDP1
SCHEMBL6245212 0.77 CYP3A4 (0.64) RAB9ANPC1CYP3A4ADRA2ATDP1
SCHEMBL14518104 0.77 NPC1 (0.48) RAB9ANPC1CYP3A4ADRA2ATDP1
SCHEMBL22755750 0.77 NPC1 (0.59) RAB9ANPC1CYP3A4ADRA2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103848931-B Catalyst system with three metallocenes for producing polymers with broad molecular weight distribution 切弗朗菲利浦化学公司 2020-03-17 CN disclosed
EP-2443160-B1 OLIGOMERIZATION OF ALPHA OLEFINS USING METALLOCENE-SSA CATALYST SYSTEMS AND USE OF THE RESULTANT POLYALPHAOLEFINS TO PREPARE LUBRICANT BLENDS CHEVRON PHILLIPS CHEMICAL CO LP (US) 2019-08-14 EP disclosed
EP-2692762-B1 ELECTRICALLY CONDUCTIVE COMPOSITION, ELECTRICALLY CONDUCTIVE FILM USING SAID COMPOSITION AND PRODUCTION METHOD THEREFOR FUJIFILM CORP (JP) 2017-09-27 EP disclosed
US-9745230-B2 Oligomerization of alpha olefins using metallocene-SSA catalyst systems and use of the resultant polyalphaolefins to prepare lubricant blends CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2017-08-29 US disclosed
US-20160264493-A1 Oligomerization of Alpha Olefins Using Metallocene-SSA Catalyst Systems and Use of the Resultant Polyalphaolefins to Prepare Lubricant Blends CHEVRON PHILLIPS CHEMICAL COMPANY LP 2016-09-15 US disclosed
US-9445501-B2 Electrically conductive composition, electrically conductive film using the composition and a method of producing the same FUJIFILM CORPORATION (JP) 2016-09-13 US disclosed
CN-103676508-B Electrophotographic photosensitive element, handle box and electronic photographing device 佳能株式会社 2016-08-17 CN disclosed
CN-103676507-B Electrophotographic photosensitive element, handle box and electronic photographing device 佳能株式会社 2016-08-10 CN disclosed
US-9334203-B2 Oligomerization of alpha olefins using metallocene-SSA catalyst systems and use of the resultant polyalphaolefins to prepare lubricant blends CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2016-05-10 US disclosed
EP-2128910-B1 ORGANIC EL DEVICE AND DISPLAY IDEMITSU KOSAN CO (JP) 2016-03-09 EP disclosed
EP-0422900-B1 Organic nonlinear optical material and nonlinear optical element TOSHIBA KK (JP) 1994-03-16 EP disclosed
US-5279921-A Pattern formation resist and pattern formation method KABUSHIKI KAISHA TOSHIBA (JP) 1994-01-18 US disclosed
EP-0422900-A2 Organic nonlinear optical material and nonlinear optical element KABUSHIKI KAISHA TOSHIBA (JP) 1991-04-17 EP disclosed
US-4830944-A Function separated photosensitive member having a diphenylamine derivative disazo charge generation material CANON KABUSHIKI KAISHA (JP) 1989-05-16 US disclosed
US-4592984-A Laminated structure containing charge transfer and charge generating compounds CANON KABUSHIKI KAISHA (JP) 1986-06-03 US disclosed
US-4456671-A Electrophotographic photosensitive member having a photosensitive layer containing a hydrazone compound CANON KABUSHIKI KAISHA (JP) 1984-06-26 US disclosed
US-4420548-A Electrophotographic member with hydrazone or ketazine compounds CANON KABUSHIKI KAISHA (JP) 1983-12-13 US disclosed
US-4399207-A Electrophotographic photosensitive member with hydrazone compound CANON KABUSHIKI KAISHA (JP) 1983-08-16 US disclosed
US-4391889-A Electrophotographic photosensitive member with benzimidazole ring containing hydrazones CANON KABUSHIKI KAISHA (JP) 1983-07-05 US disclosed
US-4390611-A Electrophotographic photosensitive azo pigment containing members CANON KABUSHIKI KAISHA (JP) 1983-06-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160264493-A1 Oligomerization of Alpha Olefins Using Metallocene-SSA Catalyst Systems and Use of the Resultant Polyalphaolefins to Prepare Lubricant Blends SAE1, MACO1, MSMO1 RAB9A 4646/4885NPC1 2774/4885CYP3A4 1959/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.