Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10053360 | 0.91 | LMNA (0.34) | LMNASMN1; SMN2RAB9AALDH1A1GAA | |
| SCHEMBL12724669 | 0.84 | LMNA (0.36) | LMNASMN1; SMN2RAB9AALDH1A1GAA | |
| SCHEMBL1634766 | 0.80 | RAB9A (0.36) | LMNASMN1; SMN2RAB9AALDH1A1NR3C1 | |
| SCHEMBL1236175 | 0.80 | RAF1 (0.31) | LMNASMN1; SMN2RAB9AALDH1A1GAA | |
| SCHEMBL10053357 | 0.80 | SMN1; SMN2 (0.33) | LMNASMN1; SMN2RAB9AALDH1A1GAA | |
| SCHEMBL12724679 | 0.77 | LMNA (0.36) | LMNASMN1; SMN2RAB9AALDH1A1GAA | |
| SCHEMBL10872717 | 0.77 | LMNA (0.38) | LMNASMN1; SMN2RAB9AALDH1A1GAA | |
| SCHEMBL10053361 | 0.76 | AR (0.32) | ALDH1A1 | |
| SCHEMBL23940126 | 0.74 | RAB9A (0.31) | LMNASMN1; SMN2RAB9AALDH1A1NR3C1 | |
| SCHEMBL8183276 | 0.74 | LMNA (0.36) | LMNASMN1; SMN2RAB9AALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7932211-B2 | 4-(4-trifluoromethyl-3-thiobenzoyl)pyrazoles and their use as herbicides | BAYER CROPSCIENCE AG (DE) | 2011-04-26 | — | — | US | disclosed |
| EP-2137160-B1 | 4-(4-TRIFLUOROMETHYL-3-THIOBENZOYL)PYRAZOLES AND USE THEREOF AS HERBICIDES | BAYER CROPSCIENCE AG (DE) | 2010-10-27 | — | — | EP | disclosed |
| EP-2137160-A1 | 4-(4-TRIFLUOROMETHYL-3-THIOBENZOYL)PYRAZOLES, AND USE THEREOF AS HERBICIDES | Bayer CropScience AG (DE) | 2009-12-30 | — | — | EP | disclosed |
| US-20090069184-A1 | 4-(4-trifluoromethyl-3-thiobenzoyl)pyrazoles and their use as herbicides | BAYER CROPSCIENCE AG (DE) | 2009-03-12 | — | — | US | disclosed |
| WO-2008125214-A1 | 4-(4-TRIFLUOROMETHYL-3-THIOBENZOYL)PYRAZOLES, AND USE THEREOF AS HERBICIDES | BAYER CROPSCIENCE AG (DE) | 2008-10-23 | — | — | WO | disclosed |
| EP-1980556-A1 | 4-(4-trifluor methyl-3-thiobenzoyl) pyrazoles and their application as herbicides | Bayer CropScience AG (DE) | 2008-10-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090069184-A1 | 4-(4-trifluoromethyl-3-thiobenzoyl)pyrazoles and their use as herbicides | TH, DDT, CYP4X1 | LMNA 4746/4885SMN1; SMN2 4667/4885RAB9A 2045/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.