Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAF1 | P04049 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.30 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | CTSS | P25774 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10053360 | 0.86 | LMNA (0.34) | SMN1; SMN2RAB9ANR3C1LMNAGAA | |
| SCHEMBL1637412 | 0.80 | LMNA (0.34) | SMN1; SMN2RAB9ANR3C1LMNAGAA | |
| SCHEMBL1236184 | 0.78 | GAA (0.32) | LMNAGAAALDH1A1NPSR1CTSS | |
| SCHEMBL9076511 | 0.76 | KDM4E (0.34) | SMN1; SMN2RAB9ALMNAGAAALDH1A1 | |
| SCHEMBL12724669 | 0.75 | LMNA (0.36) | RAF1SMN1; SMN2RAB9ANR3C1LMNA | |
| SCHEMBL1962808 | 0.74 | MEN1 (0.39) | SMN1; SMN2RAB9ALMNAALDH1A1 | |
| SCHEMBL12724679 | 0.73 | LMNA (0.36) | SMN1; SMN2RAB9ALMNAGAAALDH1A1 | |
| SCHEMBL10053361 | 0.72 | AR (0.32) | ALDH1A1 | |
| SCHEMBL1634766 | 0.72 | RAB9A (0.36) | SMN1; SMN2RAB9ANR3C1LMNAALDH1A1 | |
| SCHEMBL27524777 | 0.71 | LMNA (0.44) | SMN1; SMN2RAB9ALMNAGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2475646-B1 | 4-(3-ALKYLTHIOBENZOYL)PYRAZOLES AND THEIR USE AS HERBICIDES | BAYER IP GMBH (DE) | 2017-06-21 | — | — | EP | disclosed |
| US-8288319-B2 | 4-(3-alkylthiobenzoyl)pyrazoles and their use as herbicides | BAYER CROPSCIENCE AG (DE) | 2012-10-16 | — | — | US | disclosed |
| EP-2475646-A1 | 4-(3-ALKYLTHIOBENZOYL)PYRAZOLES AND USE THEREOF AS HERBICIDES | Bayer CropScience AG (DE) | 2012-07-18 | — | — | EP | disclosed |
| US-20110045980-A1 | 4-(3-ALKYLTHIOBENZOYL)PYRAZOLES AND THEIR USE AS HERBICIDES | BAYER CROPSCIENCE AG (DE) | 2011-02-24 | — | — | US | disclosed |
| WO-2011012246-A1 | 4-(3-ALKYLTHIOBENZOYL)PYRAZOLES AND USE THEREOF AS HERBICIDES | BAYER CROPSCIENCE AG (DE) | 2011-02-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110045980-A1 | 4-(3-ALKYLTHIOBENZOYL)PYRAZOLES AND THEIR USE AS HERBICIDES | CYP4X1, PRDX4, PRXL2A | RAF1 1215/4885SMN1; SMN2 4799/4885TMPRSS4 4087/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.