Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | ERO1A | Q96HE7 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15611017 | 0.91 | LMNA (0.36) | LMNATHRBCYP2C19F2CYP3A4 | |
| SCHEMBL15607833 | 0.90 | LMNA (0.40) | LMNATHRBCYP2C19F2CYP3A4 | |
| SCHEMBL15607861 | 0.83 | F2 (0.39) | LMNATHRBCYP2C19F2CYP3A4 | |
| SCHEMBL15607892 | 0.81 | LMNA (0.39) | LMNATHRBCYP2C19F2CYP3A4 | |
| SCHEMBL15607822 | 0.81 | LMNA (0.38) | LMNATHRBCYP2C19F2CYP3A4 | |
| SCHEMBL16375036 | 0.78 | F2 (0.39) | F2ERO1AKMT2AMEN1MAPT | |
| SCHEMBL15607862 | 0.76 | ALDH1A1 (0.34) | LMNATHRBCYP2C19F2CYP3A4 | |
| SCHEMBL15607829 | 0.76 | KMT2A (0.41) | LMNATHRBCYP2C19CYP3A4CYP2D6 | |
| SCHEMBL16375032 | 0.75 | F2 (0.33) | LMNATHRBCYP2C19F2CYP3A4 | |
| SCHEMBL367133 | 0.73 | LMNA (0.68) | LMNATHRBCYP2C19F2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150010474-A1 | Compounds And Methods For Selective Imaging And/Or Ablation | AUCKLAND UNISERVICES LTD (NL) | 2015-01-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150010474-A1 | Compounds And Methods For Selective Imaging And/Or Ablation | CBR1, CBR3, BLVRB | LMNA 4469/4885THRB 1824/4885CYP2C19 340/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.