SCHEMBL16375202

SCHEMBL16375202

O=C(NC(Cc1ccc(-c2ncc(-c3ccccc3)cn2)cc1)C(=O)NCCCO)c1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 1/20 0.58
▸ KMT2A Q03164 1/20 0.54
▸ GRIA1 P42261 2/20 0.53
▸ CTSS P25774 7/20 0.53
▸ CTSK P43235 4/20 0.53
▸ CTSB P07858 3/20 0.53
▸ CTSL P07711 9/20 0.50
▸ TACR2 P21452 1/20 0.48
▸ KLKB1 P03952 2/20 0.46
▸ CTSV O60911 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16375232 0.88 L3MBTL1 (0.59) L3MBTL1KMT2AGRIA1CTSSCTSK
SCHEMBL16375201 0.88 CTSL (0.53) L3MBTL1KMT2AGRIA1CTSSCTSK
SCHEMBL16375212 0.83 PTPN1 (0.57) —
SCHEMBL16375200 0.81 MME (0.53) L3MBTL1CTSSCTSKCTSBCTSL
SCHEMBL17994241 0.80 L3MBTL1 (0.57) L3MBTL1KMT2AGRIA1CTSSCTSK
SCHEMBL16375204 0.79 CTSS (0.50) L3MBTL1CTSSCTSKCTSBCTSL
SCHEMBL16306220 0.79 GCGR (0.56) L3MBTL1CTSSCTSKCTSBCTSL
SCHEMBL16375233 0.77 CTSL (0.54) L3MBTL1KMT2ACTSSCTSKCTSB
SCHEMBL15037188 0.77 MME (0.53) L3MBTL1CTSSCTSKCTSB
SCHEMBL22448948 0.77 MME (0.53) L3MBTL1CTSSCTSKCTSB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150011527-A1 NOVEL GLP-1 RECEPTOR MODULATORS RECEPTOS LLC 2015-01-08 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150011527-A1 NOVEL GLP-1 RECEPTOR MODULATORS GLP1R, GIPR, NPY1R L3MBTL1 771/4885KMT2A 4232/4885GRIA1 424/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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