Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | ACE | P12821 | 16/20 | 0.51 |
| ▸ | ACE2 | Q9BYF1 | 10/20 | 0.51 |
| ▸ | MME | P08473 | 1/20 | 0.47 |
| ▸ | MMEL1 | Q495T6 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17994248 | 0.92 | ACE (0.50) | TSHRACEACE2MMEMMEL1 | |
| SCHEMBL16375206 | 0.89 | TSHR (0.63) | TSHRACEACE2 | |
| SCHEMBL17834576 | 0.86 | ACE (0.49) | TSHRACEACE2MMEMMEL1 | |
| SCHEMBL16375207 | 0.85 | RAB9A (0.43) | — | |
| SCHEMBL16375205 | 0.83 | HSPA1A (0.43) | MME | |
| SCHEMBL17994250 | 0.82 | ACE (0.63) | TSHRACEACE2 | |
| SCHEMBL16375214 | 0.82 | HSPA5 (0.46) | TSHR | |
| SCHEMBL16375213 | 0.81 | HSPA1A (0.53) | ACEACE2MME | |
| SCHEMBL15037081 | 0.81 | ACE (0.46) | TSHRACEACE2MMEMMEL1 | |
| SCHEMBL15037086 | 0.81 | ACE (0.46) | TSHRACEACE2MMEMMEL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170313717-A1 | NOVEL GLP-1 RECEPTOR MODULATORS | RECEPTOS LLC | 2017-11-02 | — | — | US | disclosed |
| US-9598430-B2 | GLP-1 receptor modulators | CELGENE INTERNATIONAL II SÀRL (CH) | 2017-03-21 | — | — | US | disclosed |
| US-20160214993-A1 | NOVEL GLP-1 RECEPTOR MODULATORS | RECEPTOS LLC | 2016-07-28 | — | — | US | disclosed |
| US-20150011527-A1 | NOVEL GLP-1 RECEPTOR MODULATORS | RECEPTOS LLC | 2015-01-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170313717-A1 | NOVEL GLP-1 RECEPTOR MODULATORS | GLP1R, GIPR, NPY1R | TSHR 45/4885ACE 3137/4885ACE2 3162/4885 |
| US-20160214993-A1 | NOVEL GLP-1 RECEPTOR MODULATORS | GLP1R, GIPR, NPY1R | TSHR 45/4885ACE 3137/4885ACE2 3162/4885 |
| US-20150011527-A1 | NOVEL GLP-1 RECEPTOR MODULATORS | GLP1R, GIPR, NPY1R | TSHR 45/4885ACE 3137/4885ACE2 3162/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.