Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPA5 | P11021 | 2/20 | 0.46 |
| ▸ | HSPA1A | P0DMV8 | 1/20 | 0.46 |
| ▸ | HSPA9 | P38646 | 1/20 | 0.46 |
| ▸ | HSPA2 | P54652 | 1/20 | 0.46 |
| ▸ | PYGL | P06737 | 1/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | HPGDS | O60760 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16375205 | 0.93 | HSPA1A (0.43) | HSPA5HSPA1AHSPA9HSPA2CTSL | |
| SCHEMBL17994253 | 0.92 | HSPA5 (0.43) | HSPA5HSPA1AHSPA9HSPA2PYGL | |
| SCHEMBL16375207 | 0.92 | RAB9A (0.43) | HSPA5HSPA1AHSPA9HSPA2CTSL | |
| SCHEMBL16375215 | 0.89 | PYGL (0.48) | PYGLCTSLS1PR4S1PR1S1PR5 | |
| SCHEMBL17994245 | 0.85 | HSPA1A (0.41) | HSPA5HSPA1AHSPA9HSPA2CTSL | |
| SCHEMBL17834564 | 0.85 | PYGL (0.41) | PYGLHPGDSDPP4S1PR4S1PR1 | |
| SCHEMBL16375213 | 0.84 | HSPA1A (0.53) | HSPA5HSPA1AHSPA9HSPA2CTSL | |
| SCHEMBL17994246 | 0.84 | RAB9A (0.43) | HSPA5HSPA1AHSPA9HSPA2CTSL | |
| SCHEMBL16375210 | 0.82 | TSHR (0.51) | TSHR | |
| SCHEMBL16375209 | 0.81 | KMT2A (0.47) | CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170313717-A1 | NOVEL GLP-1 RECEPTOR MODULATORS | RECEPTOS LLC | 2017-11-02 | — | — | US | disclosed |
| US-9598430-B2 | GLP-1 receptor modulators | CELGENE INTERNATIONAL II SÀRL (CH) | 2017-03-21 | — | — | US | disclosed |
| US-20160214993-A1 | NOVEL GLP-1 RECEPTOR MODULATORS | RECEPTOS LLC | 2016-07-28 | — | — | US | disclosed |
| US-20150011527-A1 | NOVEL GLP-1 RECEPTOR MODULATORS | RECEPTOS LLC | 2015-01-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170313717-A1 | NOVEL GLP-1 RECEPTOR MODULATORS | GLP1R, GIPR, NPY1R | HSPA5 3669/4885HSPA1A 2012/4885HSPA9 2536/4885 |
| US-20160214993-A1 | NOVEL GLP-1 RECEPTOR MODULATORS | GLP1R, GIPR, NPY1R | HSPA5 3669/4885HSPA1A 2012/4885HSPA9 2536/4885 |
| US-20150011527-A1 | NOVEL GLP-1 RECEPTOR MODULATORS | GLP1R, GIPR, NPY1R | HSPA5 3669/4885HSPA1A 2012/4885HSPA9 2536/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.