Sugi Predict

Sugi Predict / Compounds / Methyl 3-Chloro-4-Methoxybenzoate

Methyl 3-Chloro-4-Methoxybenzoate

Methyl 3-Chloro-4-Methoxybenzoate

SCHEMBL1637523

COC(=O)c1ccc(OC)c(Cl)c1

nearest known ligand 0.69

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 6/20 0.69
▸ NPC1 O15118 3/20 0.69
▸ RAB9A P51151 3/20 0.69
▸ MEN1 O00255 3/20 0.69
▸ MAPT P10636 2/20 0.69
▸ SMN1; SMN2 Q16637 2/20 0.69
▸ TAS1R3 Q7RTX0 6/20 0.55
▸ TAS1R1 Q7RTX1 6/20 0.55
▸ GLA P06280 1/20 0.55
▸ ALDH1A1 P00352 3/20 0.54
▸ HTT P42858 1/20 0.54
▸ KCNH2 Q12809 1/20 0.54
▸ TP53 P04637 1/20 0.54
▸ CYP1A2 P05177 1/20 0.54
▸ CYP3A4 P08684 1/20 0.54
▸ CYP2D6 P10635 1/20 0.54
▸ ALOX15 P16050 1/20 0.54
▸ CYP2C19 P33261 1/20 0.54
▸ LMNA P02545 1/20 0.52
▸ CA12 O43570 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methyl 3-Chloro-4-Methoxybenzoate SCHEMBL31296522 1.00 KMT2A (0.69) KMT2ANPC1RAB9AMEN1MAPT
SCHEMBL30685741 0.87 SMN1; SMN2 (0.56) KMT2ANPC1RAB9AMEN1MAPT
SCHEMBL27842396 0.87 SMN1; SMN2 (0.56) KMT2ANPC1RAB9AMEN1MAPT
SCHEMBL2253933 0.85 MAPT (0.62) KMT2ANPC1RAB9AMEN1MAPT
SCHEMBL11575925 0.85 CYP1A2 (0.68) KMT2ANPC1RAB9AMEN1MAPT
SCHEMBL15921171 0.85 KMT2A (0.57) KMT2ANPC1RAB9AMEN1MAPT
SCHEMBL516420 0.84 KMT2A (0.53) KMT2ANPC1RAB9AMEN1MAPT
SCHEMBL10543265 0.84 S1PR4 (0.56) KMT2ANPC1RAB9AMEN1MAPT
SCHEMBL28560816 0.84 MAPT (0.56) KMT2ANPC1RAB9AMEN1MAPT
SCHEMBL308170 0.83 TPMT (0.69) KMT2ANPC1RAB9AMEN1TAS1R3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2516479-B1 NEW INTERNAL AND EXTERNAL DONOR COMPOUNDS FOR OLEFIN POLYMERIZATION CATALYSTS BASF CORP (US) 2016-04-20 — — EP claimed
EP-2516479-A2 NEW INTERNAL AND EXTERNAL DONOR COMPOUNDS FOR OLEFIN POLYMERIZATION CATALYSTS BASF Corporation (US) 2012-10-31 — — EP claimed
CN-102762602-A New internal and external donor compounds for olefin polymerization catalysts BASF CORP 2012-10-31 — — CN claimed
US-8211819-B2 Internal and external donor compounds for olefin polymerization catalysts BASF CORPORATION (US) 2012-07-03 — — US claimed
WO-2011084691-A2 NEW INTERNAL AND EXTERNAL DONOR COMPOUNDS FOR OLEFIN POLYMERIZATION CATALYSTS BASF CORPORATION (US) 2011-07-14 — — WO claimed
US-20110152481-A1 Internal and external donor compounds for olefin polymerization catalysts BASF CATALYSTS LLC (US) 2011-06-23 — — US claimed
EP-4559908-A1 HETEROARYL DERIVATIVE COMPOUND AND USE THEREOF S2CBio Inc. (KR) 2025-05-28 — — EP disclosed
WO-2024058617-A1 ANTIVIRAL USE OF HETEROARYL DERIVATIVE COMPOUND 일동제약(주) 2024-03-21 — — WO disclosed
WO-2024019541-A1 HETEROARYL DERIVATIVE COMPOUND AND USE THEREOF 일동제약(주) 2024-01-25 — — WO disclosed
US-20220386582-A1 METHOD AND DEVICE TO TRAP ACARIDS DOMOBIOS (BE) 2022-12-08 — — US disclosed
EP-4032896-A1 THIAZOLOPYRIMIDONES AS INHIBITORS OF DDR1/2 AND THERAPEUTIC USES THEREOF Fundación del Sector Público Estatal Centro Nacional de Investigaciones Oncológicas Carlos III (F.S.P. CNIO) (ES) 2022-07-27 — — EP disclosed
US-20210161130-A1 COMPOSITIONS FOR ATTRACTING PESTS AND USES THEREOF DOMOBIOS (BE) 2021-06-03 — — US disclosed
EP-3813530-A1 COMPOSITIONS FOR ATTRACTING PESTS AND USES THEREOF Domobios (BE) 2021-05-05 — — EP disclosed
US-20050171109-A1 Tetrahydronaphthalene derivatives, process for their production and their use as anti-inflammatory agents BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) 2005-08-04 — — US disclosed
WO-2005034939-A1 1-AMINO-2-OXY-SUBSTITUTED TETRAHYDRONAPHTALENE DERIVATIVES, METHODS FOR THE PRODUCTION THEREOF, AND THEIR USE AS ANTIPHLOGISTICS SCHERING AKTIENGESELLSCHAFT (DE) 2005-04-21 — — WO disclosed
US-20040249148-A1 Imidazotriazines for use as phosphodiesterase inhibitors BAYER HEALTHCARE AG (DE) 2004-12-09 — — US disclosed
EP-1404677-A1 IMIDAZOTRIAZINES FOR USE AS PHOSPHODIESTERASE INHIBITORS Bayer HealthCare AG (DE) 2004-04-07 — — EP disclosed
WO-2003000693-A1 IMIDAZOTRIAZINES FOR USE AS PHOSPHODIESTERASE INHIBITORS BAYER HEALTHCARE AG (DE) 2003-01-03 — — WO disclosed
EP-1223170-A1 PYRIMIDINE-5-CARBOXAMIDE COMPOUNDS, PROCESS FOR PRODUCING THE SAME AND USE THEREOF Takeda Chemical Industries, Ltd. (JP) 2002-07-17 — — EP disclosed
US-3975537-A SUBSTITUTED BENZOFURANS SMITH KLINE (US) 1976-08-17 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040249148-A1 Imidazotriazines for use as phosphodiesterase inhibitors PDE3A, PDE2A, PDE4A KMT2A 1817/4885NPC1 3110/4885RAB9A 1995/4885
US-20050171109-A1 Tetrahydronaphthalene derivatives, process for their production and their use as anti-inflammatory agents TNF, DHPS, PTGES KMT2A 4643/4885NPC1 1696/4885RAB9A 2917/4885
US-20210161130-A1 COMPOSITIONS FOR ATTRACTING PESTS AND USES THEREOF ACAT1, ATL3, NISCH KMT2A 2474/4885NPC1 962/4885RAB9A 3065/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.