Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 13/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 3/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18386673 | 0.79 | ACHE (0.54) | ACHEKEAP1NFE2L2EPHX2 | |
| SCHEMBL23153172 | 0.79 | ACHE (0.54) | ACHEKEAP1NFE2L2EPHX2 | |
| SCHEMBL16202934 | 0.79 | — | — | |
| SCHEMBL19000408 | 0.76 | ACHE (0.58) | ACHEEPHX2 | |
| SCHEMBL22064745 | 0.76 | ACHE (0.58) | ACHEEPHX2 | |
| SCHEMBL28316408 | 0.76 | ACHE (0.64) | ACHEEPHX2 | |
| SCHEMBL14494732 | 0.76 | ACHE (0.51) | ACHEKEAP1NFE2L2EPHX2 | |
| SCHEMBL16351803 | 0.75 | KEAP1 (0.36) | ACHEKEAP1NFE2L2EPHX2 | |
| SCHEMBL16202936 | 0.75 | — | — | |
| SCHEMBL10639023 | 0.74 | ACHE (0.61) | ACHEEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150004113-A1 | SILOXANE POLYMERS WITH A CENTRAL POLYSILOXANE POLYMER BLOCK WITH TERMINAL ORGANOFUNCTIONAL RADICALS COMPRISING UREA AND/OR CARBAMATE GROUPS AND AMINO ACID RADICALS | EVONIK DEGUSSA GMBH (DE) | 2015-01-01 | — | — | US | disclosed |
| US-20150004112-A1 | SILOXANE POLYMERS WITH A CENTRAL POLYSILOXANE POLYMER BLOCK WITH ORGANOFUNCTIONAL RADICALS EACH HAVING AT LEAST TWO BIVALENT GROUPS SELECTED FROM UREA AND/OR CARBAMATE GROUPS AND AT LEAST ONE UV/VIS CHROMOPHORE AS RADICAL | EVONIK INDUSTRIES AG (DE) | 2015-01-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150004112-A1 | SILOXANE POLYMERS WITH A CENTRAL POLYSILOXANE POLYMER BLOCK WITH ORGANOFUNCTIONAL RADICALS EACH HAVING AT LEAST TWO BIVALENT GROUPS SELECTED FROM UREA AND/OR CARBAMATE GROUPS AND AT LEAST ONE UV/VIS CHROMOPHORE AS RADICAL | CCNI, UBE2I, CCNB1 | ACHE 2875/4885KEAP1 2116/4885NFE2L2 2011/4885 |
| US-20150004113-A1 | SILOXANE POLYMERS WITH A CENTRAL POLYSILOXANE POLYMER BLOCK WITH TERMINAL ORGANOFUNCTIONAL RADICALS COMPRISING UREA AND/OR CARBAMATE GROUPS AND AMINO ACID RADICALS | UBE2I, CCNI, IL4I1 | ACHE 4294/4885KEAP1 2251/4885NFE2L2 2350/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.