SCHEMBL1637549

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1635675	0.95	CYP11B1 (0.44)	CYP11B1KDM4EHPGDMAPTTSHR
	SCHEMBL12069425	0.95	CYP11B1 (0.46)	CYP11B1KDM4EHPGDMAPTTSHR
	SCHEMBL1636392	0.94	CYP11B1 (0.42)	CYP11B1KDM4EHPGDMAPTTSHR
	SCHEMBL12070716	0.93	CYP11B1 (0.45)	CYP11B1KDM4EHPGDMAPTTSHR
	SCHEMBL1635755	0.93	GPR84 (0.43)	CYP11B1KDM4EHPGDMAPTTSHR
	SCHEMBL22141151	0.92	KDM4E (0.49)	CYP11B1KDM4EHPGDMAPTTSHR
	SCHEMBL1637321	0.91	GPR84 (0.42)	CYP11B1KDM4EHPGDMAPTTSHR
	SCHEMBL25050984	0.90	CYP11B1 (0.41)	CYP11B1KDM4EHPGDMAPTTSHR
	SCHEMBL1636341	0.90	CYP11B1 (0.42)	CYP11B1KDM4EHPGDMAPTTSHR
	SCHEMBL25052707	0.89	CYP11B1 (0.40)	CYP11B1KDM4EHPGDMAPTTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.