SCHEMBL16376362

SCHEMBL16376362

COCCOCCOCCCCC(=O)ON1C(=O)CCC1=O

nearest known ligand 0.43

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.43
HPGD P15428 1/20 0.43
HTT P42858 1/20 0.43
EPHX2 P34913 2/20 0.35
ALDH1A1 P00352 3/20 0.35
KMT2A Q03164 1/20 0.34
MAPT P10636 1/20 0.33
PSMB8 P28062 2/20 0.31
ALOX12 P18054 1/20 0.31
PSMB5 P28074 1/20 0.30
GAA P10253 1/20 0.30
KAT2B Q92831 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20008754 1.00 SMN1; SMN2 (0.43) SMN1; SMN2HPGDHTTEPHX2ALDH1A1
SCHEMBL17753479 1.00 SMN1; SMN2 (0.43) SMN1; SMN2HPGDHTTEPHX2ALDH1A1
SCHEMBL3460141 0.99 SMN1; SMN2 (0.45) SMN1; SMN2HPGDHTTEPHX2ALDH1A1
SCHEMBL3460109 0.99 SMN1; SMN2 (0.45) SMN1; SMN2HPGDHTTEPHX2ALDH1A1
SCHEMBL13029835 0.99 SMN1; SMN2 (0.45) SMN1; SMN2HPGDHTTEPHX2ALDH1A1
SCHEMBL3625357 0.99 SMN1; SMN2 (0.45) SMN1; SMN2HPGDHTTEPHX2ALDH1A1
SCHEMBL24136289 0.95 SMN1; SMN2 (0.41) SMN1; SMN2HPGDHTTEPHX2ALDH1A1
SCHEMBL25962486 0.95 SMN1; SMN2 (0.41) SMN1; SMN2HPGDHTTEPHX2ALDH1A1
SCHEMBL915308 0.95 SMN1; SMN2 (0.41) SMN1; SMN2HPGDHTTEPHX2ALDH1A1
SCHEMBL14117834 0.91 SMN1; SMN2 (0.43) SMN1; SMN2HPGDHTTALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12016922-B2 Stabilized aqueous antibody compositions ARECOR LIMITED (GB) 2024-06-25 US disclosed
US-20160022783-A1 POLYALKYLENE OXIDE VALERATE HEMOGLOBIN CONJUGATES SCHINDLER, WILLIAM 2016-01-28 US disclosed
US-20150010548-A1 Stabilized Aqueous Antibody Compositions ARECOR LIMITED (GB) 2015-01-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160022783-A1 POLYALKYLENE OXIDE VALERATE HEMOGLOBIN CONJUGATES HBZ, HBB, HBG1 SMN1; SMN2 3443/4885HPGD 483/4885HTT 509/4885
US-20150010548-A1 Stabilized Aqueous Antibody Compositions IGLV6-57, FCGRT, PA2G4 SMN1; SMN2 1144/4885HPGD 4558/4885HTT 227/4885
US-12016922-B2 Stabilized aqueous antibody compositions IGLV6-57, FCGRT, PA2G4 SMN1; SMN2 1188/4885HPGD 4568/4885HTT 221/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.