SCHEMBL915308

SCHEMBL915308

COCCOCCOCCOCCCC(=O)ON1C(=O)CCC1=O

nearest known ligand 0.41

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.41
HPGD P15428 1/20 0.41
HTT P42858 1/20 0.41
ALDH1A1 P00352 1/20 0.34
MAPT P10636 1/20 0.34
KMT2A Q03164 1/20 0.32
PSMB8 P28062 2/20 0.32
EPHX2 P34913 2/20 0.31
PSMB5 P28074 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24136289 1.00 SMN1; SMN2 (0.41) SMN1; SMN2HPGDHTTALDH1A1MAPT
SCHEMBL25962486 1.00 SMN1; SMN2 (0.41) SMN1; SMN2HPGDHTTALDH1A1MAPT
SCHEMBL20008754 0.95 SMN1; SMN2 (0.43) SMN1; SMN2HPGDHTTALDH1A1MAPT
SCHEMBL17753479 0.95 SMN1; SMN2 (0.43) SMN1; SMN2HPGDHTTALDH1A1MAPT
SCHEMBL16376362 0.95 SMN1; SMN2 (0.43) SMN1; SMN2HPGDHTTALDH1A1MAPT
SCHEMBL13029835 0.94 SMN1; SMN2 (0.45) SMN1; SMN2HPGDHTTALDH1A1MAPT
SCHEMBL3460141 0.94 SMN1; SMN2 (0.45) SMN1; SMN2HPGDHTTALDH1A1MAPT
SCHEMBL3460109 0.94 SMN1; SMN2 (0.45) SMN1; SMN2HPGDHTTALDH1A1MAPT
SCHEMBL3625357 0.94 SMN1; SMN2 (0.45) SMN1; SMN2HPGDHTTALDH1A1MAPT
SCHEMBL127754 0.92 SMN1; SMN2 (0.33) SMN1; SMN2HPGDHTTKMT2APSMB8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105801686-B Insulin-oligomer conjugates, formulations and uses thereof 比奥孔有限公司 2020-04-07 CN disclosed
EP-2626368-B1 Insulin-oligomer conjugates, formulations and uses thereof BIOCON LTD (IN) 2016-12-21 EP disclosed
US-9101596-B2 Cation complexes of insulin compound conjugates, formulations and uses thereof BIOCON LIMITED (IN) 2015-08-11 US disclosed
US-9102758-B2 Insulin-oligomer conjugates, formulations and uses thereof BIOCON LIMITED (IN) 2015-08-11 US disclosed
US-9102758-B2 Insulin-oligomer conjugates, formulations and uses thereof BIOCON LIMITED (IN) 2015-08-11 US disclosed
US-9102758-B2 Insulin-oligomer conjugates, formulations and uses thereof BIOCON LIMITED (IN) 2015-08-11 US disclosed
US-9101596-B2 Cation complexes of insulin compound conjugates, formulations and uses thereof BIOCON LIMITED (IN) 2015-08-11 US disclosed
US-9101596-B2 Cation complexes of insulin compound conjugates, formulations and uses thereof BIOCON LIMITED (IN) 2015-08-11 US disclosed
EP-1773878-B1 INSULIN-OLIGOMER CONJUGATES, FORMULATIONS AND USES THEREOF BIOCON LTD (IN) 2015-03-04 EP disclosed
US-8563685-B2 Fatty acid formulations and oral delivery of proteins and peptides, and uses thereof BIOCON LIMITED (IN) 2013-10-22 US disclosed
US-20100105605-A1 FATTY ACID FORMULATIONS AND ORAL DELIVERY OF PROTEINS AND PEPTIDES, AND USES THEREOF RADHAKRISHNAN BALASINGAM 2010-04-29 US disclosed
US-20100105605-A1 FATTY ACID FORMULATIONS AND ORAL DELIVERY OF PROTEINS AND PEPTIDES, AND USES THEREOF RADHAKRISHNAN BALASINGAM 2010-04-29 US disclosed
US-7605123-B2 Fatty acid formulations for oral delivery of proteins and peptides, and uses thereof BIOCON LTD. (IN) 2009-10-20 US disclosed
US-7605123-B2 Fatty acid formulations for oral delivery of proteins and peptides, and uses thereof BIOCON LTD. (IN) 2009-10-20 US disclosed
US-7605123-B2 Fatty acid formulations for oral delivery of proteins and peptides, and uses thereof BIOCON LTD. (IN) 2009-10-20 US disclosed
EP-1773878-A2 INSULIN-OLIGOMER CONJUGATES, FORMULATIONS AND USES THEREOF Nobex Corporation (US) 2007-04-18 EP disclosed
WO-2006014673-A2 INSULIN-OLIGOMER CONJUGATES, FORMULATIONS AND USES THEREOF NOBEX CORPORATION (US) 2006-02-09 WO disclosed
US-20060018874-A1 Fatty acid formulations for oral delivery of proteins and peptides, and uses thereof BIOCON LIMITED (IN) 2006-01-26 US disclosed
US-20060019873-A1 Cation complexes of insulin compound conjugates, formulations and uses thereof BIOCON LIMITED (IN) 2006-01-26 US disclosed
US-20060019874-A1 Cation complexes of insulin compund conjugates, formulation and uses thereof NOBEX CORPORATION 2006-01-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060019873-A1 Cation complexes of insulin compound conjugates, formulations and uses thereof GPR119, INSR, IAPP SMN1; SMN2 3078/4885HPGD 3925/4885HTT 2890/4885
US-20100105605-A1 FATTY ACID FORMULATIONS AND ORAL DELIVERY OF PROTEINS AND PEPTIDES, AND USES THEREOF FABP2, SLC27A1, SLC27A2 SMN1; SMN2 1534/4885HPGD 4005/4885HTT 1498/4885
US-20060018874-A1 Fatty acid formulations for oral delivery of proteins and peptides, and uses thereof FABP2, SLC27A1, SLC27A2 SMN1; SMN2 1537/4885HPGD 3961/4885HTT 1496/4885
US-20060019874-A1 Cation complexes of insulin compund conjugates, formulation and uses thereof INSR, GPR119, IAPP SMN1; SMN2 1606/4885HPGD 4150/4885HTT 614/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.