SCHEMBL16376382

SCHEMBL16376382

c1ccc(-c2cc(-c3c4ccccc4c(-c4ccc5c6c(cccc46)-c4ccccc4O5)c4ccccc34)c3ccccc3c2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.47
MAPK1 P28482 3/20 0.47
ATM Q13315 2/20 0.47
MAOA P21397 1/20 0.35
MAOB P27338 1/20 0.35
ALDH1A1 P00352 3/20 0.34
HPGD P15428 3/20 0.34
TSHR P16473 2/20 0.34
HSD17B10 Q99714 2/20 0.34
L3MBTL1 Q9Y468 2/20 0.34
CASP1 P29466 1/20 0.34
HIF1A Q16665 1/20 0.34
MAPT P10636 2/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
MPI P34949 1/20 0.33
GPR84 Q9NQS5 5/20 0.32
TP53 P04637 1/20 0.32
NFKB1 P19838 1/20 0.32
NFKB2 Q00653 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23758712 0.86 MAPK1 (0.53) KDM4EMAPK1ATMMAOAMAOB
SCHEMBL16376366 0.86 MAPK1 (0.59) KDM4EMAPK1ATMMAOAMAOB
SCHEMBL19600429 0.85 KDM4E (0.47) KDM4EMAPK1ATMMAOAMAOB
SCHEMBL16376408 0.84 MAPK1 (0.54) KDM4EMAPK1ATMMAOAMAOB
SCHEMBL23109623 0.84 MAPK1 (0.54) KDM4EMAPK1ATMMAOAMAOB
SCHEMBL16376376 0.84 KDM4E (0.49) KDM4EMAPK1ATMMAOAMAOB
SCHEMBL22971812 0.84 KDM4E (0.49) KDM4EMAPK1ATMMAOAMAOB
SCHEMBL16376365 0.84 MAPK1 (0.61) KDM4EMAPK1ATMMAOAMAOB
SCHEMBL16558360 0.84 ATM (0.43) KDM4EMAPK1ATML3MBTL1MAPT
SCHEMBL16558358 0.84 ATM (0.43) KDM4EMAPK1ATML3MBTL1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240023436-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO.,LTD. (JP) 2024-01-18 US disclosed
US-20240023436-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO.,LTD. (JP) 2024-01-18 US disclosed
US-11839148-B2 Organic electroluminescent element and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2023-12-05 US disclosed
US-20230209996-A1 ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC APPARATUS IDEMITSU KOSAN CO.,LTD. (JP) 2023-06-29 US disclosed
US-20230209996-A1 ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC APPARATUS IDEMITSU KOSAN CO.,LTD. (JP) 2023-06-29 US disclosed
US-20230209998-A1 ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC APPARATUS IDEMITSU KOSAN CO.,LTD. (JP) 2023-06-29 US disclosed
US-20230209998-A1 ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC APPARATUS IDEMITSU KOSAN CO.,LTD. (JP) 2023-06-29 US disclosed
US-20220393113-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO.,LTD. (JP) 2022-12-08 US disclosed
US-11094886-B2 Organic electroluminescent element and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2021-08-17 US disclosed
US-20210083193-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO.,LTD. (JP) 2021-03-18 US disclosed
US-10256416-B2 Compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2019-04-09 US disclosed
US-20150001479-A1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2015-01-01 US disclosed
US-20150001479-A1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2015-01-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240023436-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE EED, EML4, ESR1 KDM4E 494/4885MAPK1 2256/4885ATM 2500/4885
US-10256416-B2 Compound and organic light-emitting device including the same ALDH1A2, AOX1, OR10J3 KDM4E 2779/4885MAPK1 617/4885ATM 3093/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.