SCHEMBL1637696

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1637694	1.00	ALOX5 (0.51)	ALOX5PRKDCGGPS1PIK3CDPIK3CA
	SCHEMBL1637386	0.95	ALOX5 (0.53)	ALOX5PRKDCGGPS1PIK3CDPIK3CA
	SCHEMBL1637311	0.95	ALOX5 (0.53)	ALOX5PRKDCGGPS1PIK3CDPIK3CA
	SCHEMBL24090374	0.94	ALOX5 (0.57)	ALOX5PRKDCGGPS1PIK3CDPIK3CB
	SCHEMBL1637204	0.93	ALOX5 (0.48)	ALOX5PRKDCGGPS1PIK3CDPIK3CA
	SCHEMBL1637698	0.92	ALOX5 (0.50)	ALOX5PRKDCGGPS1PIK3CDPIK3CA
	SCHEMBL1636214	0.92	ALOX5 (0.50)	ALOX5PRKDCGGPS1PIK3CDPIK3CA
	SCHEMBL1635732	0.92	ALOX5 (0.53)	ALOX5PRKDCGGPS1PIK3CDPIK3CA
	SCHEMBL1637357	0.91	ALOX5 (0.54)	ALOX5PRKDCGGPS1PIK3CDPIK3CA
	SCHEMBL17057204	0.89	ALOX5 (0.57)	ALOX5PRKDCGGPS1ALDH1A1PIM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.