Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | GUSB | P08236 | 1/20 | 0.39 |
| ▸ | GLS | O94925 | 1/20 | 0.38 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16378341 | 0.95 | EPHX2 (0.40) | HTR7GLSGGPS1CNR1ACHE | |
| SCHEMBL16369323 | 0.95 | EPHX2 (0.38) | HTR7GLSGGPS1CNR1ACHE | |
| SCHEMBL16378338 | 0.94 | HTR7 (0.41) | HTR7GUSBGLSSLC6A2CYP19A1 | |
| SCHEMBL16378335 | 0.91 | GGPS1 (0.39) | GLSGGPS1CNR1ACHECNR2 | |
| SCHEMBL16369318 | 0.90 | GLS (0.38) | HTR7GUSBGLSSLC6A2CYP19A1 | |
| SCHEMBL16378334 | 0.90 | GLS (0.38) | HTR7GUSBGLSCNR1ACHE | |
| SCHEMBL16378228 | 0.89 | GUSB (0.43) | HTR7GUSBGLSSLC6A2CYP19A1 | |
| SCHEMBL16378235 | 0.89 | GLS (0.38) | HTR7GUSBGLSSLC6A2CA9 | |
| SCHEMBL16378339 | 0.88 | CYP19A1 (0.41) | GGPS1CNR1ACHECNR2SLC6A2 | |
| SCHEMBL16378230 | 0.85 | GUSB (0.40) | HTR7GUSBGLSSLC6A2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8921328-B2 | E-selectin antagonists | GLYCOMIMETICS, INC. (US) | 2014-12-30 | — | — | US | disclosed |