SCHEMBL16378339

SCHEMBL16378339

CCCCCc1cn(Cn2ccc3cc([N+](=O)[O-])ccc32)nn1

nearest known ligand 0.41

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 6/20 0.41
GGPS1 O95749 2/20 0.39
CNR1 P21554 1/20 0.38
ACHE P22303 1/20 0.38
CNR2 P34972 1/20 0.38
MIF P14174 1/20 0.37
SLC6A2 P23975 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16378335 0.97 GGPS1 (0.39) CYP19A1GGPS1CNR1ACHECNR2
SCHEMBL16378337 0.93 SLC6A2 (0.39) CYP19A1SLC6A2
SCHEMBL16378229 0.88 SLC6A2 (0.40) CYP19A1SLC6A2
SCHEMBL16378336 0.88 HTR7 (0.40) CYP19A1GGPS1CNR1ACHECNR2
SCHEMBL16369323 0.87 EPHX2 (0.38) GGPS1CNR1ACHECNR2SLC6A2
SCHEMBL16378341 0.87 EPHX2 (0.40) GGPS1CNR1ACHECNR2
SCHEMBL16378334 0.83 GLS (0.38) CYP19A1CNR1ACHECNR2SLC6A2
SCHEMBL16369318 0.83 GLS (0.38) CYP19A1SLC6A2
SCHEMBL16378338 0.83 HTR7 (0.41) CYP19A1SLC6A2
SCHEMBL16369321 0.82 CYP19A1 (0.46) CYP19A1GGPS1MIF

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8921328-B2 E-selectin antagonists GLYCOMIMETICS, INC. (US) 2014-12-30 US disclosed