Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | TNF | P01375 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 6/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16770596 | 1.00 | LMNA (0.47) | LMNATNFALDH1A1TSHRTDP1 | |
| SCHEMBL16383651 | 0.92 | MEN1 (0.47) | LMNATNFALDH1A1TSHRTDP1 | |
| SCHEMBL17359607 | 0.88 | LMNA (0.45) | LMNATNFALDH1A1TSHRTDP1 | |
| SCHEMBL18239897 | 0.86 | LMNA (0.47) | LMNAALDH1A1TSHRTDP1L3MBTL1 | |
| SCHEMBL8271920 | 0.85 | LGALS9 (0.41) | LMNATNFALDH1A1TSHRTDP1 | |
| SCHEMBL15483270 | 0.83 | PTPN1 (0.56) | LMNATNFALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL14817669 | 0.83 | PTPN1 (0.56) | LMNATNFALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL10182633 | 0.83 | PTPN1 (0.56) | LMNATNFALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL8271923 | 0.83 | MEN1 (0.45) | LMNAALDH1A1TSHRTDP1L3MBTL1 | |
| SCHEMBL18239780 | 0.82 | LMNA (0.43) | LMNAALDH1A1TSHRTDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015002954-A1 | SYNTHETIC OLIGOSACCHARIDES FOR P. AERUGINOSA VACCINE | SYNGLYCO PHARMACEUTICALS, INC. (US) | 2015-01-08 | — | — | WO | disclosed |