SCHEMBL1637850

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1635833	0.94	AHR (0.47)	AHRMAOAMAPTKDM4EALDH1A1
	SCHEMBL24362987	0.92	AHR (0.52)	AHRMAOAMAPTKDM4EALDH1A1
	SCHEMBL1636812	0.92	KMT2A (0.46)	AHRMAOAMAPTKDM4EALDH1A1
	SCHEMBL12175698	0.90	AHR (0.57)	AHRMAOAMAPTKDM4EALDH1A1
	SCHEMBL16133297	0.88	MAPT (0.55)	AHRMAOAMAPTKDM4EALDH1A1
	SCHEMBL16904367	0.88	AHR (0.55)	AHRMAOAMAPTKDM4EALDH1A1
	SCHEMBL25052970	0.88	PLA2G2A (0.49)	AHRMAOAMAPTKDM4EALDH1A1
	SCHEMBL17231570	0.86	AHR (0.53)	AHRMAOAMAPTKDM4EALDH1A1
	SCHEMBL25050934	0.86	MAPT (0.53)	AHRMAOAMAPTKDM4EALDH1A1
	SCHEMBL17231580	0.86	AHR (0.53)	AHRMAOAMAPTKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.