Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 3/20 | 0.32 |
| ▸ | NOS3 | P29474 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.32 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14927020 | 0.77 | GRIN2D (0.41) | ALDH1A1KDM4EMAPTGRIN2DGRIN3B | |
| SCHEMBL14927071 | 0.71 | CTSS (0.37) | NOS2ALDH1A1KDM4EMAPTNOS1 | |
| SCHEMBL12070768 | 0.67 | KDM4E (0.52) | ALDH1A1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL14927016 | 0.67 | ASIC1 (0.42) | ALDH1A1KDM4EMAPTGRIN2DGRIN3B | |
| SCHEMBL14927018 | 0.66 | KIF11 (0.39) | ALDH1A1KDM4EMAPTGRIN2DGRIN3B | |
| SCHEMBL14927107 | 0.66 | MAPT (0.37) | ALDH1A1MEN1KMT2AKDM4EPOLB | |
| SCHEMBL14927013 | 0.63 | PLAU (0.49) | ALDH1A1MEN1KMT2AKDM4EPOLB | |
| SCHEMBL14927019 | 0.63 | CTSS (0.38) | ALDH1A1KDM4EMAPTGRIN2DGRIN3B | |
| SCHEMBL13776830 | 0.63 | MEN1 (0.51) | ALDH1A1MEN1KMT2AKDM4EPOLB | |
| SCHEMBL14123232 | 0.62 | MEN1 (0.50) | ALDH1A1MEN1KMT2AKDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8933096-B2 | Antimicrobial agents | Rugers, The State University of New Jersey (US) | 2015-01-13 | — | — | US | disclosed |