Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | CNKSR1 | Q969H4 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16342350 | 0.84 | CA1 (0.50) | TTRDPP4MAPTCA12CA1 | |
| SCHEMBL16342351 | 0.84 | CA1 (0.50) | TTRDPP4MAPTCA12CA1 | |
| SCHEMBL3913993 | 0.79 | MAPT (0.49) | TTRDPP4MAPTCYP3A4HCAR2 | |
| SCHEMBL3913996 | 0.79 | MAPT (0.49) | TTRDPP4MAPTCYP3A4HCAR2 | |
| SCHEMBL32677337 | 0.74 | CYP3A4 (0.44) | TTRDPP4MAPTCYP3A4HCAR2 | |
| SCHEMBL6297111 | 0.72 | MAPT (0.46) | TTRDPP4MAPTCYP3A4HCAR2 | |
| SCHEMBL6297110 | 0.72 | MAPT (0.46) | TTRDPP4MAPTCYP3A4HCAR2 | |
| SCHEMBL19899935 | 0.71 | CYP3A4 (0.43) | TTRDPP4MAPTCYP3A4HCAR2 | |
| SCHEMBL3921298 | 0.71 | HCAR2 (0.55) | TTRDPP4MAPTCYP3A4HCAR2 | |
| SCHEMBL2794488 | 0.71 | HCAR2 (0.55) | TTRDPP4MAPTCYP3A4HCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9233911-B2 | Cu-mediated annulation for the production of 1-amino-2-naphthalenecarboxylic acid derivatives | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2016-01-12 | — | — | US | disclosed |
| US-20150011781-A1 | Cu-Mediated Annulation for the Production of 1-Amino-2-Naphthalenecarboxylic Acid Derivatives | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2015-01-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150011781-A1 | Cu-Mediated Annulation for the Production of 1-Amino-2-Naphthalenecarboxylic Acid Derivatives | DDC, AOC2, AOC1 | TTR 1267/4885DPP4 1729/4885MAPT 1886/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.