SCHEMBL163798

SCHEMBL163798

CCNS(=O)(=O)c1cccc(OCF)c1C#N

nearest known ligand 0.38

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.38
ALDH1A1 P00352 1/20 0.38
GAA P10253 1/20 0.38
SLC22A12 Q96S37 3/20 0.38
DRD1 P21728 3/20 0.38
CCR4 P51679 1/20 0.38
GLA P06280 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36
ADRB1 P08588 1/20 0.35
TRPV4 Q9HBA0 3/20 0.35
ALOX5AP P20292 2/20 0.34
FEN1 P39748 2/20 0.34
HSD17B10 Q99714 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30753930 0.85 ALDH1A1 (0.50) KDM4EALDH1A1GAASLC22A12CCR4
SCHEMBL162306 0.85 ALDH1A1 (0.50) KDM4EALDH1A1GAASLC22A12CCR4
SCHEMBL168868 0.83 SLC22A12 (0.38) KDM4EALDH1A1GAASLC22A12CCR4
SCHEMBL29572421 0.83 SLC22A12 (0.38) KDM4EALDH1A1GAASLC22A12CCR4
Ethane SCHEMBL16670063 0.80 DRD1 (0.43) ALDH1A1SLC22A12DRD1CCR4NPC1
SCHEMBL14568178 0.79 CCR4 (0.49) KDM4EALDH1A1GAASLC22A12CCR4
SCHEMBL5007597 0.77 ALDH1A1 (0.41) KDM4EALDH1A1SLC22A12GLASMN1; SMN2
SCHEMBL5323794 0.71 SLC22A12 (0.39) SLC22A12CCR4ADRB1TRPV4
SCHEMBL5520773 0.70 ALDH1A1 (0.41) KDM4EALDH1A1GAASLC22A12CCR4
SCHEMBL175274 0.69 SMN1; SMN2 (0.41) KDM4EALDH1A1GAASLC22A12GLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 379 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3060043-B1 PESTICIDAL COMPOSITIONS AND RELATED METHODS CORTEVA AGRISCIENCE LLC (US) 2025-11-26 EP claimed
US-20250313704-A1 ALGICIDAL ORGANISMS PRO FARM GROUP, INC. 2025-10-09 US claimed
EP-3537878-B1 ALGICIDAL ORGANISMS PRO FARM GROUP INC (US) 2023-11-22 EP claimed
US-20210282405-A1 ALGICIDAL ORGANISMS MARRONE BIO INNOVATIONS, INC. (US) 2021-09-16 US claimed
US-RE48057-E1 Pesticidal compositions and related methods DOW AGROSCIENCES LLC (US) 2020-06-23 US claimed
CN-107072206-B Pesticidal compositions and related methods 美国陶氏益农公司 2020-02-21 CN claimed
EP-3145312-B1 PESTICIDAL COMPOSITIONS AND RELATED METHODS DOW AGROSCIENCES LLC (US) 2019-11-20 EP claimed
EP-3537878-A1 ALGICIDAL ORGANISMS Marrone Bio Innovations, Inc. (US) 2019-09-18 EP claimed
EP-3062619-B1 PESTICIDAL COMPOSITIONS AND RELATED METHODS DOW AGROSCIENCES LLC (US) 2019-07-24 EP claimed
EP-2731430-B1 PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO DOW AGROSCIENCES LLC (US) 2019-04-03 EP claimed
WO-2012177813-A1 PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO DOW AGROSCIENCES LLC (US) 2012-12-27 WO claimed
US-20120329649-A1 PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO DOW AGROSCIENCES LLC 2012-12-27 US claimed
US-20120172218-A1 PESTICIDAL COMPOSITIONS DOW AGROSCIENCES LLC (US) 2012-07-05 US claimed
WO-2012061290-A2 PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO DOW AGROSCIENCES LLC (US) 2012-05-10 WO claimed
WO-2012061288-A1 PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO DOW AGROSCIENCES LLC (US) 2012-05-10 WO claimed
US-20120110702-A1 Pesticidal Compositions and Processes Related Thereto CORTEVA AGRISCIENCE LLC 2012-05-03 US claimed
US-20120110701-A1 PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO DOW AGROSCIENCES LLC (US) 2012-05-03 US claimed
EP-2427191-A1 PESTICIDAL COMPOSITIONS Dow AgroSciences LLC (US) 2012-03-14 EP claimed
US-20100292253-A1 PESTICIDAL COMPOSITIONS DOW AGROSCIENCES LLC (US) 2010-11-18 US claimed
WO-2010129497-A1 PESTICIDAL COMPOSITIONS DOW AGROSCIENCES LLC (US) 2010-11-11 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120172218-A1 PESTICIDAL COMPOSITIONS ACHE, DDT, PTMS KDM4E 1172/4885ALDH1A1 2560/4885GAA 1671/4885
US-20120110701-A1 PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO ACHE, AGPS, DDT KDM4E 3198/4885ALDH1A1 1177/4885GAA 1260/4885
US-20100292253-A1 PESTICIDAL COMPOSITIONS ACHE, DDT, PRDX6 KDM4E 3250/4885ALDH1A1 1636/4885GAA 2045/4885
US-20120329649-A1 PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO ACHE, DDT, PTMS KDM4E 3388/4885ALDH1A1 854/4885GAA 1052/4885
US-20120110702-A1 Pesticidal Compositions and Processes Related Thereto ACHE, DDT, PTMS KDM4E 3338/4885ALDH1A1 1073/4885GAA 1186/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.