SCHEMBL175274

SCHEMBL175274

CCNS(=O)(=O)c1ccc(F)c(OC)c1C#N

nearest known ligand 0.42

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.41
GLA P06280 1/20 0.41
ALDH1A1 P00352 4/20 0.39
KDM4E B2RXH2 1/20 0.39
GAA P10253 1/20 0.39
ACLY P53396 1/20 0.36
POLB P06746 1/20 0.35
LMNA P02545 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
SLC22A12 Q96S37 3/20 0.34
ALOX5AP P20292 1/20 0.33
FEN1 P39748 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2C19 P33261 1/20 0.33
USP2 O75604 1/20 0.33
TRPV4 Q9HBA0 1/20 0.33
BRAF P15056 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30753927 0.86 EPAS1 (0.35) SMN1; SMN2GLAALDH1A1KDM4EGAA
SCHEMBL164626 0.86 EPAS1 (0.35) SMN1; SMN2GLAALDH1A1KDM4EGAA
SCHEMBL28241123 0.85 SMN1; SMN2 (0.43) SMN1; SMN2GLAALDH1A1KDM4EGAA
SCHEMBL4729448 0.81 TRPV4 (0.41) ACLYSLC22A12TRPV4
SCHEMBL28724645 0.75 ALDH1A1 (0.36) SMN1; SMN2GLAALDH1A1KDM4EGAA
SCHEMBL30753930 0.75 ALDH1A1 (0.50) SMN1; SMN2GLAALDH1A1KDM4EGAA
SCHEMBL162306 0.75 ALDH1A1 (0.50) SMN1; SMN2GLAALDH1A1KDM4EGAA
SCHEMBL186103 0.72 SLC6A3 (0.36) ALDH1A1KDM4ELMNACYP1A2CYP3A4
SCHEMBL29518830 0.72 SLC6A3 (0.36) ALDH1A1KDM4ELMNACYP1A2CYP3A4
SCHEMBL5520773 0.70 ALDH1A1 (0.41) SMN1; SMN2GLAALDH1A1KDM4EGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 409 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3537878-B1 ALGICIDAL ORGANISMS PRO FARM GROUP INC (US) 2023-11-22 EP claimed
US-20210282405-A1 ALGICIDAL ORGANISMS MARRONE BIO INNOVATIONS, INC. (US) 2021-09-16 US claimed
US-RE48057-E1 Pesticidal compositions and related methods DOW AGROSCIENCES LLC (US) 2020-06-23 US claimed
CN-107072206-B Pesticidal compositions and related methods 美国陶氏益农公司 2020-02-21 CN claimed
EP-3145312-B1 PESTICIDAL COMPOSITIONS AND RELATED METHODS DOW AGROSCIENCES LLC (US) 2019-11-20 EP claimed
EP-3537878-A1 ALGICIDAL ORGANISMS Marrone Bio Innovations, Inc. (US) 2019-09-18 EP claimed
EP-3062619-B1 PESTICIDAL COMPOSITIONS AND RELATED METHODS DOW AGROSCIENCES LLC (US) 2019-07-24 EP claimed
EP-2731430-B1 PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO DOW AGROSCIENCES LLC (US) 2019-04-03 EP claimed
US-20180110222-A1 Pesticidal Mixtures Comprising Cyanosulfoximine Compounds BASF SE (DE) 2018-04-26 US claimed
EP-2934135-B1 PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO DOW AGROSCIENCES LLC (US) 2018-01-31 EP claimed
EP-2427191-A1 PESTICIDAL COMPOSITIONS Dow AgroSciences LLC (US) 2012-03-14 EP claimed
JP-2012500824-A 2012-01-12 JP claimed
US-20110160054-A1 Pesticidal Mixtures Comprising Cyanosulfoximine Compounds and Spinetoram BASF SE (DE) 2011-06-30 US claimed
EP-2320741-A2 PESTICIDAL MIXTURES COMPRISING CYANOSULFOXIMINE COMPOUNDS AND SPINETORAM BASF SE (DE) 2011-05-18 EP claimed
US-20100292253-A1 PESTICIDAL COMPOSITIONS DOW AGROSCIENCES LLC (US) 2010-11-18 US claimed
WO-2010129497-A1 PESTICIDAL COMPOSITIONS DOW AGROSCIENCES LLC (US) 2010-11-11 WO claimed
US-20100120616-A1 Pesticidal Mixtures Comprising Cyanosulfoximine Compounds BASF SE (DE) 2010-05-13 US claimed
WO-2010023171-A2 PESTICIDAL MIXTURES COMPRISING CYANOSULFOXIMINE COMPOUNDS AND SPINETORAM BASF SE (DE) 2010-03-04 WO claimed
EP-2114163-A2 PESTICIDAL MIXTURES COMPRISING CYANOSULFOXIMINE COMPOUNDS BASF SE (DE) 2009-11-11 EP claimed
WO-2008125410-A2 PESTICIDAL MIXTURES COMPRISING CYANOSULFOXIMINE COMPOUNDS BASF SE (DE) 2008-10-23 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100292253-A1 PESTICIDAL COMPOSITIONS ACHE, DDT, PRDX6 SMN1; SMN2 2870/4885GLA 1803/4885ALDH1A1 1636/4885
US-20100120616-A1 Pesticidal Mixtures Comprising Cyanosulfoximine Compounds CHRM3, CHRM5, CHRM2 SMN1; SMN2 3965/4885GLA 2818/4885ALDH1A1 2624/4885
US-20180110222-A1 Pesticidal Mixtures Comprising Cyanosulfoximine Compounds CHRM3, CHRM5, CHRM2 SMN1; SMN2 4411/4885GLA 3051/4885ALDH1A1 2730/4885
US-20110160054-A1 Pesticidal Mixtures Comprising Cyanosulfoximine Compounds and Spinetoram CHRM3, CHRM2, BRS3 SMN1; SMN2 2749/4885GLA 2941/4885ALDH1A1 3669/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.