Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | TDO2 | P48775 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CCR6 | P51684 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16382048 | 0.76 | IDO1 (0.43) | IDO1TDO2RAB9AKCNMA1SMN1; SMN2 | |
| SCHEMBL11696314 | 0.74 | KCNMA1 (0.51) | RAB9AKCNMA1SMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL22383440 | 0.74 | NPC1 (0.46) | RAB9AKCNMA1SMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL20938974 | 0.74 | SMN1; SMN2 (0.42) | RAB9AKCNMA1SMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL10357737 | 0.71 | CA12 (0.51) | RAB9AKCNMA1SMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL28099573 | 0.71 | IDO1 (0.55) | IDO1TDO2RAB9AKCNMA1SMN1; SMN2 | |
| SCHEMBL12204569 | 0.71 | RAB9A (0.56) | RAB9AKCNMA1SMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL14944391 | 0.71 | FGFR1 (0.57) | RAB9AKCNMA1SMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL12204565 | 0.69 | SMN1; SMN2 (0.62) | RAB9AKCNMA1SMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL3977744 | 0.69 | TDP1 (0.56) | IDO1TDO2RAB9AKCNMA1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3124481-A1 | ANDROGEN RECEPTOR MODULATORS AND USES THEREOF | Aragon Pharmaceuticals, Inc. (US) | 2017-02-01 | — | — | EP | disclosed |
| EP-2824102-A1 | Androgen receptor modulators and uses thereof | Aragon Pharmaceuticals, Inc. (US) | 2015-01-14 | — | — | EP | disclosed |