SCHEMBL16385447

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL15685954	1.00	ALDH1A1 (0.39)	ALDH1A1HSD17B10BCL2L1MAPK1HPGD
	SCHEMBL29776672	1.00	ALDH1A1 (0.39)	ALDH1A1HSD17B10BCL2L1MAPK1HPGD
	SCHEMBL6212117	1.00	ALDH1A1 (0.39)	ALDH1A1HSD17B10BCL2L1MAPK1HPGD
	SCHEMBL15038424	1.00	ALDH1A1 (0.39)	ALDH1A1HSD17B10BCL2L1MAPK1HPGD
	SCHEMBL24910350	0.98	ALDH1A1 (0.40)	ALDH1A1HSD17B10BCL2L1MAPK1HPGD
	SCHEMBL15685949	0.98	ALDH1A1 (0.40)	ALDH1A1HSD17B10BCL2L1MAPK1HPGD
	SCHEMBL16385730	0.98	ALDH1A1 (0.40)	ALDH1A1HSD17B10BCL2L1MAPK1HPGD
	SCHEMBL29776698	0.98	ALDH1A1 (0.40)	ALDH1A1HSD17B10BCL2L1MAPK1HPGD
	SCHEMBL16385506	0.98	ALDH1A1 (0.40)	ALDH1A1HSD17B10BCL2L1MAPK1HPGD
	SCHEMBL17811573	0.98	PTGS2 (0.38)	ALDH1A1HSD17B10BCL2L1MAPK1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.