Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.49 |
| ▸ | RXRB | P28702 | 1/20 | 0.49 |
| ▸ | RXRG | P48443 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16384996 | 0.88 | ALDH1A1 (0.45) | RXRARXRBRXRGALDH1A1SLC22A12 | |
| SCHEMBL17788267 | 0.85 | MRGPRX4 (0.53) | SLC22A12FFAR4SMN1; SMN2MEN1NPC1 | |
| SCHEMBL17788271 | 0.85 | SLC22A12 (0.44) | ALDH1A1SLC22A12TDP1L3MBTL1FFAR4 | |
| SCHEMBL16385008 | 0.82 | ALDH1A1 (0.51) | RXRARXRBRXRGALDH1A1TDP1 | |
| SCHEMBL17788278 | 0.82 | SLC22A12 (0.41) | ALDH1A1SLC22A12FFAR4NPSR1SMN1; SMN2 | |
| SCHEMBL16385462 | 0.81 | ALDH1A1 (0.40) | RXRARXRBRXRGALDH1A1SLC22A12 | |
| SCHEMBL16385318 | 0.81 | RXRA (0.44) | RXRARXRBRXRGALDH1A1SLC22A12 | |
| SCHEMBL17788277 | 0.81 | MRGPRX4 (0.47) | ALDH1A1SLC22A12FFAR4NPSR1PTGER1 | |
| SCHEMBL16385322 | 0.77 | SLC22A12 (0.54) | RXRARXRBRXRGSLC22A12L3MBTL1 | |
| SCHEMBL17788264 | 0.77 | MRGPRX4 (0.55) | SLC22A12FFAR4SMN1; SMN2MEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015005499-A1 | TETRAZOLINONE COMPOUND AND USE THEREOF | 住友化学株式会社 (JP) | 2015-01-15 | — | — | WO | disclosed |