Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | RXRB | P28702 | 1/20 | 0.40 |
| ▸ | RXRG | P48443 | 1/20 | 0.40 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.38 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17788393 | 0.88 | MRGPRX4 (0.46) | ALDH1A1FFAR4MEN1KMT2A | |
| SCHEMBL17788400 | 0.87 | MAPT (0.37) | ALDH1A1SLC22A12NPSR1FFAR4 | |
| SCHEMBL17788410 | 0.84 | MRGPRX4 (0.35) | ALDH1A1SLC22A12NPSR1FFAR4 | |
| SCHEMBL17788402 | 0.84 | MRGPRX4 (0.42) | ALDH1A1SLC22A12FFAR4 | |
| SCHEMBL16385607 | 0.81 | RXRA (0.49) | ALDH1A1RXRARXRBRXRGSGMS2 | |
| SCHEMBL16384996 | 0.80 | ALDH1A1 (0.45) | ALDH1A1RXRARXRBRXRGSGMS2 | |
| SCHEMBL17191223 | 0.80 | CASP3 (0.32) | ALDH1A1L3MBTL1 | |
| SCHEMBL16920936 | 0.79 | MRGPRX4 (0.49) | ALDH1A1SLC22A12FFAR4MEN1KMT2A | |
| SCHEMBL17788417 | 0.79 | MRGPRX4 (0.38) | RXRARXRBRXRGNPSR1L3MBTL1 | |
| SCHEMBL16920950 | 0.79 | SLC22A12 (0.43) | SGMS2SLC22A12NPSR1APEX1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015005499-A1 | TETRAZOLINONE COMPOUND AND USE THEREOF | 住友化学株式会社 (JP) | 2015-01-15 | — | — | WO | disclosed |