Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 10/20 | 0.49 |
| ▸ | HTR1B | P28222 | 9/20 | 0.49 |
| ▸ | HTR1F | P30939 | 5/20 | 0.49 |
| ▸ | HTR1A | P08908 | 4/20 | 0.49 |
| ▸ | FASN | P49327 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.40 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13478358 | 0.89 | ALDH1A1 (0.51) | FASNALDH1A1HDAC3HDAC1HDAC2 | |
| SCHEMBL2482489 | 0.84 | RAD52 (0.42) | FASNALDH1A1 | |
| SCHEMBL26640838 | 0.76 | HTR1D (0.47) | HTR1DHTR1BHTR1FHTR1AALDH1A1 | |
| SCHEMBL10126893 | 0.75 | WDR5 (0.56) | ALDH1A1 | |
| SCHEMBL27903672 | 0.73 | HTR1D (0.50) | HTR1DHTR1BHTR1FHTR1AFASN | |
| SCHEMBL522141 | 0.73 | HTR1D (0.56) | HTR1DHTR1BHTR1FALDH1A1 | |
| SCHEMBL3313895 | 0.73 | PIK3C3 (0.50) | ALDH1A1L3MBTL1 | |
| SCHEMBL10126927 | 0.73 | WDR5 (0.49) | ALDH1A1ATR | |
| SCHEMBL26040667 | 0.73 | HTR1D (0.52) | HTR1DHTR1BHTR1F | |
| SCHEMBL12073521 | 0.72 | HTR1D (0.55) | HTR1DHTR1BHTR1FALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9783524-B2 | Protein tyrosine kinase modulators and methods of use | BETTA PHARMACEUTICALS CO., LTD. (CN) | 2017-10-10 | — | — | US | disclosed |
| US-20160145237-A1 | PROTEIN TYROSINE KINASE MODULATORS AND METHODS OF USE | BETTA PHARMACEUTICALS CO., LTD (CN) | 2016-05-26 | — | — | US | disclosed |
| WO-2015003658-A1 | PROTEIN TYROSINE KINASE MODULATORS AND METHODS OF USE | BETTA PHARMACEUTICALS CO., LTD (CN) | 2015-01-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160145237-A1 | PROTEIN TYROSINE KINASE MODULATORS AND METHODS OF USE | ALK, EGFR, ERBB2 | HTR1D 3083/4885HTR1B 2574/4885HTR1F 2814/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.