SCHEMBL16387597

SCHEMBL16387597

NC(CC(Cc1ccc(OCC[18F])cc1)C(=O)O)C(=O)O

nearest known ligand 0.60

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ SLC1A1 P43005 2/20 0.60
▸ SLC1A3 P43003 1/20 0.60
▸ SLC1A2 P43004 1/20 0.60
▸ ITGB3 P05106 4/20 0.58
▸ ITGA2B P08514 4/20 0.58
▸ PTPN1 P18031 1/20 0.46
▸ GRM2 Q14416 1/20 0.42
▸ GRM3 Q14832 1/20 0.42
▸ SLC7A5 Q01650 1/20 0.42
▸ GRIK1 P39086 4/20 0.42
▸ GRIK2 Q13002 3/20 0.42
▸ PPARG P37231 1/20 0.41
▸ PPARD Q03181 1/20 0.41
▸ PPARA Q07869 1/20 0.41
▸ LTA4H P09960 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13571196 1.00 SLC1A1 (0.60) SLC1A1SLC1A3SLC1A2ITGB3ITGA2B
SCHEMBL13571139 1.00 SLC1A1 (0.60) SLC1A1SLC1A3SLC1A2ITGB3ITGA2B
SCHEMBL16387429 1.00 SLC1A1 (0.60) SLC1A1SLC1A3SLC1A2ITGB3ITGA2B
SCHEMBL13570704 1.00 SLC1A1 (0.60) SLC1A1SLC1A3SLC1A2ITGB3ITGA2B
SCHEMBL13571195 1.00 SLC1A1 (0.60) SLC1A1SLC1A3SLC1A2ITGB3ITGA2B
SCHEMBL13570786 0.93 ITGB3 (0.60) SLC1A1SLC1A3SLC1A2ITGB3ITGA2B
SCHEMBL16387427 0.93 ITGB3 (0.60) SLC1A1SLC1A3SLC1A2ITGB3ITGA2B
SCHEMBL13571323 0.93 ITGB3 (0.60) SLC1A1SLC1A3SLC1A2ITGB3ITGA2B
SCHEMBL13639612 0.93 ITGB3 (0.60) SLC1A1SLC1A3SLC1A2ITGB3ITGA2B
SCHEMBL16387596 0.93 ITGB3 (0.60) SLC1A1SLC1A3SLC1A2ITGB3ITGA2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9238631-B2 Radiolabeled amino acids for diagnostic imaging PIRAMAL IMAGING SA (CH) 2016-01-19 — — US disclosed
US-20150011773-A1 RADIOLABELED AMINO ACIDS FOR DIAGNOSTIC IMAGING PIRAMAL IMAGING SA (CH) 2015-01-08 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150011773-A1 RADIOLABELED AMINO ACIDS FOR DIAGNOSTIC IMAGING SLC1A5, SLC6A19, BCAT2 SLC1A1 15/4885SLC1A3 11/4885SLC1A2 29/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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