Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 1/20 | 0.65 |
| ▸ | MEN1 | O00255 | 7/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | PLG | P00747 | 2/20 | 0.61 |
| ▸ | KLK1 | P06870 | 2/20 | 0.61 |
| ▸ | KLK6 | Q92876 | 2/20 | 0.61 |
| ▸ | NPC1 | O15118 | 2/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | KDM4A | O75164 | 1/20 | 0.59 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.59 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.57 |
| ▸ | MITF | O75030 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18422008 | 0.85 | LDHA (0.65) | LDHAMEN1KMT2AMAPTKDM4E | |
| SCHEMBL31094235 | 0.85 | LDHA (0.65) | LDHAMEN1KMT2AMAPTKDM4E | |
| SCHEMBL10724439 | 0.85 | LDHA (0.65) | LDHAMEN1KMT2AMAPTKDM4E | |
| SCHEMBL5667713 | 0.84 | MEN1 (0.60) | LDHAMEN1KMT2AMAPTKDM4E | |
| SCHEMBL11507636 | 0.84 | LDHA (0.62) | LDHAMEN1KMT2AMAPTKDM4E | |
| SCHEMBL856182 | 0.84 | MAPT (0.50) | LDHAMEN1KMT2AMAPTKDM4E | |
| SCHEMBL7192236 | 0.84 | PLK1 (0.66) | LDHAMEN1KMT2AMAPTKDM4E | |
| SCHEMBL11102639 | 0.82 | PLG (0.58) | LDHAMEN1KMT2AMAPTKDM4E | |
| Hydrochloric Acid SCHEMBL10957126 | 0.82 | PLG (0.58) | LDHAMEN1KMT2AMAPTKDM4E | |
| SCHEMBL145153 | 0.81 | HDAC8 (0.69) | MEN1KMT2AMAPTLMNANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999001607-A2 | ENZYMATIC OXIDATION SYSTEM WITH NOVEL ENZYMATIC-EFFECT ENHANCING COMPOUNDS | CALL, KRIMHILD (DE) | 1999-01-14 | — | — | WO | claimed |
| EP-4169736-B1 | RUBBER COMPOSITION AND TIRE | BRIDGESTONE CORP (JP) | 2024-11-27 | — | — | EP | disclosed |
| CN-115702200-B | Rubber composition and tire | 株式会社普利司通 | 2024-07-30 | — | — | CN | disclosed |
| US-20240131356-A1 | COMBINATION OF INTRACELLULAR AND EXTRACELLULAR PHOTOSENSITIZERS FOR TREATMENT OF BACTERIAL INFECTION | VANDERBILT UNIVERSITY | 2024-04-25 | — | — | US | disclosed |
| EP-4284912-A1 | COMBINATION OF INTRACELLULAR AND EXTRACELLULAR PHOTOSENSITIZERS FOR TREATMENT OF BACTERIAL INFECTION | Vanderbilt University (US) | 2023-12-06 | — | — | EP | disclosed |
| US-20230312882-A1 | RUBBER COMPOSITION AND TIRE | BRIDGESTONE CORPORATION (JP) | 2023-10-05 | — | — | US | disclosed |
| WO-2023132214-A1 | CURABLE COMPOSITION AND CURED PRODUCT | 株式会社カネカ | 2023-07-13 | — | — | WO | disclosed |
| WO-2023095850-A1 | STEEL CORD-RUBBER COMPOSITE, MANUFACTURING METHOD FOR STEEL CORD-RUBBER COMPOSITE, AND TIRE | 株式会社ブリヂストン | 2023-06-01 | — | — | WO | disclosed |
| EP-4169736-A1 | RUBBER COMPOSITION AND TIRE | BRIDGESTONE CORPORATION (JP) | 2023-04-26 | — | — | EP | disclosed |
| CN-115702200-A | Rubber composition and tire | 株式会社普利司通 | 2023-02-14 | — | — | CN | disclosed |
| US-20020128292-A1 | Substituted indole-2-carboxylic acid benzylidene-hydrazides and analogs as activators of caspases and inducers of apoptosis and the use thereof | CYTOVIA, INC. | 2002-09-12 | — | — | US | disclosed |
| US-20020077423-A1 | Polymaleimide-containing rubber composition and tire | BRIDGESTONE CORPORATION | 2002-06-20 | — | — | US | disclosed |
| US-6380288-B1 | LOW HEAT GENERATION PROPERTY, AGING REISTANCE, ALSO FOR PRODUCING VIBRATION ISOLATORS, BELTS AND HOSES AS WELL AS TIRE MATERIALS SUCH AS TIRE TREADS, UNDERTREADS, CARCASSES, SIDE WALLS AND BEADS | BRIDGESTONE CORPORATION | 2002-04-30 | — | — | US | disclosed |
| EP-1199331-A1 | Polymaleimide-containing rubber composition and tire | BRIDGESTONE CORPORATION (JP) | 2002-04-24 | — | — | EP | disclosed |
| EP-1095972-A1 | Rubber composition and tire | Bridgestone Corporation (JP) | 2001-05-02 | — | — | EP | disclosed |
| EP-1083199-A1 | RUBBER COMPOSITION AND PNEUMATIC TIRE | BRIDGESTONE CORPORATION (JP) | 2001-03-14 | — | — | EP | disclosed |
| EP-0998946-A1 | Non-porphyrin compound for use as a diagnosticum and/or pharmaceutical | K.U. LEUVEN RESEARCH & DEVELOPMENT (BE) | 2000-05-10 | — | — | EP | disclosed |
| WO-2000009169-A1 | NON-PORPHYRIN COMPOUND FOR USE AS A DIAGNOSTICUM AND/OR PHARMACEUTICAL | K.U. LEUVEN RESEARCH & DEVELOPMENT (BE) | 2000-02-24 | — | — | WO | disclosed |
| EP-0909788-A1 | RUBBER COMPOSITION AND PNEUMATIC TIRES | Bridgestone Corporation (JP) | 1999-04-21 | — | — | EP | disclosed |
| WO-1999001607-A2 | ENZYMATIC OXIDATION SYSTEM WITH NOVEL ENZYMATIC-EFFECT ENHANCING COMPOUNDS | CALL, KRIMHILD (DE) | 1999-01-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020128292-A1 | Substituted indole-2-carboxylic acid benzylidene-hydrazides and analogs as activators of caspases and inducers of apoptosis and the use thereof | BAD, API5, CASP2 | LDHA 595/4885MEN1 2427/4885KMT2A 2064/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.