Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.49 |
| ▸ | LOX | P28300 | 1/20 | 0.47 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
| ▸ | USP1 | O94782 | 3/20 | 0.43 |
| ▸ | WDR48 | Q8TAF3 | 3/20 | 0.43 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
| ▸ | SYK | P43405 | 4/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.37 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.36 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17297896 | 0.83 | LOXL2 (0.49) | LOXL2LOXNOTUMIDO1USP1 | |
| SCHEMBL10259946 | 0.83 | LOXL2 (0.67) | LOXL2LOXNOTUMIDO1USP1 | |
| SCHEMBL17297769 | 0.81 | LOXL2 (0.46) | LOXL2LOXNOTUMIDO1USP1 | |
| SCHEMBL15859900 | 0.81 | LOXL2 (0.46) | LOXL2LOXNOTUMIDO1USP1 | |
| SCHEMBL16388355 | 0.80 | LOXL2 (0.67) | LOXL2LOXNOTUMIDO1MAP4K4 | |
| SCHEMBL30119999 | 0.80 | LOXL2 (0.67) | LOXL2LOXNOTUMIDO1MAP4K4 | |
| SCHEMBL17297765 | 0.80 | AAK1 (0.47) | LOXL2LOXNOTUMIDO1USP1 | |
| SCHEMBL31119651 | 0.78 | KIF11 (0.54) | LOXL2LOXNOTUMIDO1AAK1 | |
| SCHEMBL322475 | 0.77 | SYK (0.52) | LOXL2LOXNOTUMIDO1MAP4K4 | |
| SCHEMBL31375563 | 0.77 | NOTUM (0.49) | LOXL2LOXNOTUMIDO1USP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119677733-A | Bicyclic tetrahydrothiazepine derivatives | 豪夫迈·罗氏有限公司 | 2025-03-21 | — | — | CN | disclosed |