Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 9/20 | 0.37 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | PIK3C3 | Q8NEB9 | 7/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 7/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | PIK3R1 | P27986 | 4/20 | 0.34 |
| ▸ | IDH1 | O75874 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16388793 | 0.88 | PIK3CA (0.37) | MTORPIK3CAPIK3CDPIK3R1 | |
| SCHEMBL2599607 | 0.76 | PDE4B (0.39) | MTORPIK3C3PIK3CAPIK3CDPIK3R1 | |
| SCHEMBL2599671 | 0.76 | PDE4B (0.39) | MTORPIK3C3PIK3CAPIK3CDPIK3R1 | |
| SCHEMBL2599605 | 0.76 | PDE4B (0.39) | MTORPIK3C3PIK3CAPIK3CDPIK3R1 | |
| SCHEMBL2599601 | 0.76 | PIK3C3 (0.43) | MTORPIK3C3PIK3CAPIK3CD | |
| SCHEMBL2599606 | 0.76 | PIK3C3 (0.43) | MTORPIK3C3PIK3CAPIK3CD | |
| SCHEMBL2599602 | 0.76 | PIK3C3 (0.43) | MTORPIK3C3PIK3CAPIK3CD | |
| SCHEMBL2599623 | 0.74 | DHFR (0.40) | MTORPIK3CA | |
| SCHEMBL16332713 | 0.73 | CYP17A1 (0.34) | PIK3CDIDH1 | |
| SCHEMBL2599661 | 0.71 | PIK3CA (0.44) | MTORPIK3C3PIK3CAPIK3R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2571872-B1 | COMPOUNDS | TREHERNE JOHNATHAN MARK (GB) | 2014-12-31 | — | — | EP | disclosed |