Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 8/20 | 0.59 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.54 |
| ▸ | BCHE | P06276 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.47 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.47 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.44 |
| ▸ | FYN | P06241 | 1/20 | 0.44 |
| ▸ | LCK | P06239 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1759239 | 0.86 | NFE2L2 (0.49) | NFE2L2TRPA1BCHEKDM4EPTGER4 | |
| SCHEMBL1759270 | 0.83 | KDM4E (0.48) | NFE2L2TRPA1BCHEKDM4EPTGER4 | |
| SCHEMBL8406052 | 0.82 | LCK (0.48) | NFE2L2TRPA1KDM4EPTGER4PTGER3 | |
| SCHEMBL8406054 | 0.82 | LCK (0.48) | NFE2L2TRPA1KDM4EPTGER4PTGER3 | |
| SCHEMBL1759117 | 0.80 | NFE2L2 (0.51) | NFE2L2TRPA1BCHEKDM4EPTGER4 | |
| SCHEMBL1758969 | 0.79 | NFE2L2 (0.44) | NFE2L2TRPA1BCHEKDM4EPTGER4 | |
| SCHEMBL8797212 | 0.79 | CCNB2 (0.53) | NFE2L2TRPA1PTGER4PTGER3PTGER2 | |
| SCHEMBL1897191 | 0.79 | MGAM (0.45) | NFE2L2BCHEKDM4EPTGER4PTGER3 | |
| SCHEMBL8406768 | 0.78 | PTGER4 (0.56) | NFE2L2TRPA1PTGER4PTGER3PTGER2 | |
| SCHEMBL8409750 | 0.78 | PTGER4 (0.56) | NFE2L2TRPA1PTGER4PTGER3PTGER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8541521-B2 | Catalyst compounds and use thereof | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2013-09-24 | — | — | US | disclosed |
| EP-2493933-A2 | CATALYST COMPOUNDS AND USE THEREOF | ExxonMobil Chemical Patents Inc. (US) | 2012-09-05 | — | — | EP | disclosed |
| WO-2011056424-A2 | CATALYST COMPOUNDS AND USE THEREOF | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2011-05-12 | — | — | WO | disclosed |
| US-20110098427-A1 | Catalyst Compounds And Use Thereof | EXXONMOBIL CHEMICAL PATENTS INC. | 2011-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110098427-A1 | Catalyst Compounds And Use Thereof | THEM6, OPRM1, NOTUM | NFE2L2 26/4885TRPA1 426/4885BCHE 3273/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.