Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19380740 | 0.85 | DHFR (0.55) | DHFRHTTRAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL1706290 | 0.85 | DHFR (0.55) | DHFRHTTRAB9AKMT2ASMN1; SMN2 | |
| Obefazimod SCHEMBL1705888 | 0.84 | DHFR (0.54) | DHFRHTTRAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL1702468 | 0.84 | DHFR (0.58) | DHFRRAB9AKMT2ASMN1; SMN2NPC1 | |
| SCHEMBL1705361 | 0.84 | DHFR (0.54) | DHFRHTTRAB9AKMT2ASMN1; SMN2 | |
| Obefazimod SCHEMBL30729382 | 0.83 | DHFR (0.53) | DHFRHTTRAB9AKMT2ASMN1; SMN2 | |
| Obefazimod SCHEMBL29157012 | 0.83 | DHFR (0.53) | DHFRHTTRAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL18034847 | 0.82 | DHFR (0.52) | DHFRHTTRAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL1702461 | 0.82 | DHFR (0.53) | DHFRRAB9AKMT2ASMN1; SMN2NPC1 | |
| SCHEMBL7116183 | 0.81 | KDM4E (0.55) | DHFRHTTRAB9AKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015001518-A1 | BICYCLIC COMPOUNDS USEFUL FOR TREATING DISEASES CAUSED BY RETROVIRUSES | SPLICOS (FR) | 2015-01-08 | — | — | WO | disclosed |