Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 2/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.43 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.43 |
| ▸ | ABL1 | P00519 | 8/20 | 0.41 |
| ▸ | BCR | P11274 | 7/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | BRAF | P15056 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | PLK1 | P53350 | 1/20 | 0.38 |
| ▸ | CTSC | P53634 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1706290 | 0.83 | DHFR (0.55) | DHFRKCNH2SCN5ASCN9AABL1 | |
| SCHEMBL19380740 | 0.83 | DHFR (0.55) | DHFRKCNH2SCN5ASCN9AABL1 | |
| SCHEMBL16388751 | 0.82 | DHFR (0.54) | DHFRKCNH2SCN5ASCN9AABL1 | |
| SCHEMBL1705361 | 0.82 | DHFR (0.54) | DHFRKCNH2SCN5ASCN9AABL1 | |
| Obefazimod SCHEMBL1705888 | 0.82 | DHFR (0.54) | DHFRKCNH2SCN5ASCN9AABL1 | |
| SCHEMBL1702468 | 0.82 | DHFR (0.58) | DHFRKCNH2SCN5ASCN9AABL1 | |
| Obefazimod SCHEMBL29157012 | 0.81 | DHFR (0.53) | DHFRKCNH2SCN5ASCN9AABL1 | |
| Obefazimod SCHEMBL30729382 | 0.81 | DHFR (0.53) | DHFRKCNH2SCN5ASCN9AABL1 | |
| SCHEMBL1702461 | 0.80 | DHFR (0.53) | DHFRKCNH2SCN5ASCN9AABL1 | |
| SCHEMBL25941674 | 0.79 | DHFR (0.54) | DHFRKCNH2SCN5ASCN9AABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3059591-A1 | Methods for screening compounds for treating or preventing a viral infection or a virus-related condition | ABIVAX (FR) | 2016-08-24 | — | — | EP | disclosed |