Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 12/20 | 0.56 |
| ▸ | CTSK | P43235 | 9/20 | 0.56 |
| ▸ | CTSS | P25774 | 7/20 | 0.56 |
| ▸ | CTSB | P07858 | 5/20 | 0.56 |
| ▸ | CTSV | O60911 | 1/20 | 0.49 |
| ▸ | CTSF | Q9UBX1 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1199812 | 0.89 | CTSL (0.70) | CTSLCTSKCTSSCTSB | |
| SCHEMBL1199815 | 0.89 | CTSL (0.70) | CTSLCTSKCTSSCTSB | |
| SCHEMBL1200545 | 0.86 | CTSS (0.72) | CTSLCTSKCTSSCTSB | |
| SCHEMBL1200546 | 0.86 | CTSS (0.72) | CTSLCTSKCTSSCTSB | |
| SCHEMBL1199853 | 0.85 | CTSL (0.58) | CTSLCTSKCTSSCTSBCTSV | |
| SCHEMBL1199851 | 0.85 | CTSL (0.58) | CTSLCTSKCTSSCTSBCTSV | |
| SCHEMBL1272837 | 0.84 | CTSS (0.80) | CTSLCTSKCTSSCTSB | |
| SCHEMBL1272917 | 0.84 | CTSS (0.80) | CTSLCTSKCTSSCTSB | |
| SCHEMBL14315245 | 0.83 | CTSL (0.60) | CTSLCTSKCTSSCTSBCTSV | |
| SCHEMBL1200635 | 0.83 | CTSK (0.61) | CTSLCTSKCTSSCTSBCTSV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2079683-B1 | DI-FLUORO CONTAINING COMPOUNDS AS CYSTEINE PROTEASE INHIBITORS | VIROBAY INC (US) | 2015-01-21 | — | — | EP | claimed |