SCHEMBL1639189

SCHEMBL1639189

CCC(c1cccc(C(CC)[Si](OC)(OC)OC)c1C(CC)[Si](OC)(OC)OC)[Si](OC)(OC)OC

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.34
GABRA1 P14867 3/20 0.31
GABRG2 P18507 3/20 0.31
GABRB3 P28472 3/20 0.31
GABRB1 P18505 2/20 0.31
GABRA5 P31644 2/20 0.31
GABRA3 P34903 2/20 0.31
GABRA2 P47869 2/20 0.31
GABRB2 P47870 2/20 0.31
GABRA4 P48169 2/20 0.31
GABRA6 Q16445 2/20 0.31
GABRP O00591 1/20 0.31
GABRD O14764 1/20 0.31
GABRE P78334 1/20 0.31
GABRG1 Q8N1C3 1/20 0.31
GABRG3 Q99928 1/20 0.31
GABRQ Q9UN88 1/20 0.31
MCHR1 Q99705 1/20 0.31
BCHE P06276 1/20 0.31
TYR P14679 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1639304 0.86 TSHR (0.42) TSHRGABRA1GABRG2GABRB3GABRB1
SCHEMBL3345346 0.79 CA1 (0.43) TSHRBCHETYRACHECA1
SCHEMBL1639325 0.79 ESR1 (0.31) BCHETYRACHE
SCHEMBL15672822 0.79 AOC3 (0.44) TSHRCYP1A2
SCHEMBL4465341 0.78 TSHR (0.58) TSHRGABRA1GABRG2GABRB3GABRB1
SCHEMBL8161387 0.78 ALDH1A1 (0.40) TSHRMCHR1CYP1A2CYP3A4PTGS1
SCHEMBL28392081 0.77 NPC1 (0.39) TSHRHPGD
SCHEMBL6886707 0.77 TSHR (0.35) TSHR
SCHEMBL11835692 0.75 TSHR (0.34) TSHR
SCHEMBL15209649 0.74 LMNA (0.33) MCHR1BCHETYRACHELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1391476-B1 PHOTOREACTIVE COMPOSITION SEKISUI CHEMICAL CO LTD (JP) 2015-12-09 EP disclosed
US-8536242-B2 Photocurable composition SEKISUI CHEMICAL CO., LTD. (JP) 2013-09-17 US disclosed
US-20110097669-A1 PHOTOCURABLE COMPOSITION SEKISUI CHEMICAL CO., LTD. (JP) 2011-04-28 US disclosed
US-7312013-B2 Photoreactive composition SEKISUI CHEMICAL CO., LTD. (JP) 2007-12-25 US disclosed
US-20040202956-A1 a photocurable mixture of a hydrolyzable metal (silyl) compound and a reaction, polymerization or crosslinking promoter; curing; adhesives, seals, semiconductors, dielectrics, microlenses, optical fibers, color filters, gas permeable films SEKISUI CHEMICAL CO., LTD. (JP) 2004-10-14 US disclosed
EP-1391476-A1 PHOTOREACTIVE COMPOSITION SEKISUI CHEMICAL CO., LTD. (JP) 2004-02-25 EP disclosed