Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.58 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.48 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | TYR | P14679 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1639304 | 0.87 | TSHR (0.42) | TSHRGABRA1GABRB2LMNAKDM4E | |
| SCHEMBL3345346 | 0.80 | CA1 (0.43) | TSHRPOLBBCHETYRACHE | |
| SCHEMBL1765958 | 0.79 | GABRA1 (0.54) | TSHRGABRA1GABRB2POLBCA1 | |
| SCHEMBL8161387 | 0.79 | ALDH1A1 (0.40) | TSHRALDH1A1HSD17B10CYP1A2CYP3A4 | |
| SCHEMBL1639189 | 0.78 | TSHR (0.34) | TSHRGABRA1GABRB2BCHETYR | |
| SCHEMBL6886707 | 0.77 | TSHR (0.35) | TSHRNISCH | |
| SCHEMBL15672822 | 0.76 | AOC3 (0.44) | TSHRALDH1A1CYP1A2 | |
| SCHEMBL11835692 | 0.76 | TSHR (0.34) | TSHRALDH1A1 | |
| SCHEMBL2007943 | 0.76 | IRAK4 (0.44) | TSHRLMNAHPGDKDM4EALDH1A1 | |
| SCHEMBL20721726 | 0.74 | TSHR (1.00) | TSHRGABRA1GABRB2POLBBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7517925-B2 | Benzoxazines, thermosetting resins comprised thereof, and methods for use thereof | HENKEL CORPORATION (US) | 2009-04-14 | — | — | US | disclosed |
| US-20040123948-A1 | Benzoxazines, thermosetting resins comprised thereof, and methods for use thereof | LOCTITE CORPORATION | 2004-07-01 | — | — | US | disclosed |
| US-6743852-B2 | A THERMOSETTING RESIN COMPOSITION CONTAINING A BENZOXAZINE COMPOUND WITH A POLYMERIZABLE MOITY, AND A CURING AGENT | HENKEL CORPORATION | 2004-06-01 | — | — | US | disclosed |
| US-20030125551-A1 | Benzoxazines, thermosetting resins comprised thereof, and methods for use thereof | LOCTITE CORPORATION | 2003-07-03 | — | — | US | disclosed |
| WO-2003042196-A1 | BENZOXAZINESHAVING POLYMERIZABLE SIDE GROUPS, THERMOSETTING RESI NS COMPRISED THEREOF, AND METHODS FOR USE THEREOF | HENKEL CORPORATION (US) | 2003-05-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030125551-A1 | Benzoxazines, thermosetting resins comprised thereof, and methods for use thereof | TMPO, ALOX5, KDM5A | TSHR 3825/4885GABRA1 115/4885GABRB2 188/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.