Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | AGXT | P21549 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16902851 | 0.82 | TDP1 (0.87) | KDM4ETDP1MAPK1AGXTNPC1 | |
| SCHEMBL4180525 | 0.81 | KDM4E (0.61) | KDM4ETDP1MAPK1AGXTNPC1 | |
| SCHEMBL9064388 | 0.81 | KDM4E (0.61) | KDM4ETDP1MAPK1AGXTNPC1 | |
| SCHEMBL30541768 | 0.81 | CA12 (0.57) | KDM4ETDP1MAPK1AGXTNPC1 | |
| SCHEMBL470906 | 0.81 | CA12 (0.57) | KDM4ETDP1MAPK1AGXTNPC1 | |
| SCHEMBL22367610 | 0.80 | ALDH1A1 (0.44) | KDM4ETDP1MAPK1SMN1; SMN2ALDH1A1 | |
| SCHEMBL757853 | 0.80 | KDM4E (0.65) | KDM4ETDP1MAPK1AGXTNPC1 | |
| SCHEMBL29429997 | 0.80 | TDP1 (0.76) | KDM4ETDP1MAPK1AGXTNPC1 | |
| SCHEMBL8565990 | 0.80 | TDP1 (0.76) | KDM4ETDP1MAPK1AGXTNPC1 | |
| SCHEMBL1859481 | 0.80 | TDP1 (0.76) | KDM4ETDP1MAPK1AGXTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109232630-B | Copper-catalyzed synthesis method of alkenyl boron ester | 上海交通大学 | 2021-01-01 | — | — | CN | claimed |
| EP-4688743-A1 | INHIBITORS OF SPINSTER HOMOLOG 2 (SPNS2) FOR USE IN THERAPY | University of Virginia Patent Foundation (US) | 2026-02-11 | — | — | EP | disclosed |
| WO-2024206153-A1 | INHIBITORS OF SPINSTER HOMOLOG 2 (SPNS2) FOR USE IN THERAPY | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2024-10-03 | — | — | WO | disclosed |
| CN-109232630-B | Copper-catalyzed synthesis method of alkenyl boron ester | 上海交通大学 | 2021-01-01 | — | — | CN | disclosed |
| WO-2015004485-A1 | THERAPEUTIC COMPOUNDS | ISIS INNOVATION LIMITED (GB) | 2015-01-15 | — | — | WO | disclosed |