Pivalate

Pivalate

SCHEMBL1639290

CC(C)(C)C(=O)O.CC(C)CCCCCCCOC(=O)C(C)(C)C

nearest known ligand 0.40

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ACACB O00763 1/20 0.40
ACACA Q13085 1/20 0.40
RARB P10826 1/20 0.38
PRKCA P17252 4/20 0.36
KDM4C Q9H3R0 2/20 0.35
KDM4A O75164 1/20 0.35
PHF8 Q9UPP1 1/20 0.35
KDM2A Q9Y2K7 1/20 0.35
GAA P10253 2/20 0.35
NPSR1 Q6W5P4 2/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
BLM P54132 1/20 0.34
POLB P06746 1/20 0.34
NAAA Q02083 1/20 0.32
CYP4F2 P78329 1/20 0.31
CYP4A11 Q02928 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28378738 0.95 PRKCA (0.38) ACACBACACARARBPRKCAKDM4C
SCHEMBL29467087 0.95 PRKCA (0.38) ACACBACACARARBPRKCAKDM4C
SCHEMBL29365868 0.95 PRKCA (0.38) ACACBACACARARBPRKCAKDM4C
SCHEMBL22830548 0.95 PRKCA (0.38) ACACBACACARARBPRKCAKDM4C
SCHEMBL3323623 0.95 PRKCA (0.38) ACACBACACARARBPRKCAKDM4C
SCHEMBL24652860 0.95 PRKCA (0.38) ACACBACACARARBPRKCAKDM4C
SCHEMBL2523056 0.95 PRKCA (0.38) ACACBACACARARBPRKCAKDM4C
SCHEMBL10498226 0.93 PRKCA (0.39) ACACBACACARARBPRKCAKDM4C
SCHEMBL30142647 0.92 ACACB (0.51) ACACBACACARARBPRKCACYP4F2
SCHEMBL30455911 0.91 ACACB (0.54) ACACBACACARARBPRKCACYP4F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110098231-A1 Skin Cosmetic SHISEIDO COMPANY, LTD. (JP) 2011-04-28 US disclosed
EP-2168568-A1 SKIN COSMETIC Shiseido Company, Limited (JP) 2010-03-31 EP disclosed
US-20090258964-A1 Skin Cosmetic SHISEIDO COMPANY, LTD. (JP) 2009-10-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090258964-A1 Skin Cosmetic CUTA, DEGS1, ALAD ACACB 1198/4885ACACA 1184/4885RARB 537/4885
US-20110098231-A1 Skin Cosmetic CUTA, DEGS1, ALAD ACACB 1198/4885ACACA 1184/4885RARB 537/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.