Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.58 |
| ▸ | STAT1 | P42224 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3240831 | 0.96 | STAT3 (0.58) | STAT3STAT1 | |
| SCHEMBL7125994 | 0.96 | STAT3 (0.58) | STAT3STAT1 | |
| SCHEMBL1641192 | 0.96 | STAT3 (0.58) | STAT3STAT1 | |
| Water SCHEMBL4929925 | 0.96 | STAT3 (0.58) | STAT3STAT1 | |
| SCHEMBL16594232 | 0.96 | STAT3 (0.58) | STAT3STAT1 | |
| Trimethylammonium SCHEMBL28785872 | 0.91 | STAT3 (0.54) | STAT3STAT1 | |
| SCHEMBL31513281 | 0.85 | STAT3 (0.58) | STAT3STAT1 | |
| SCHEMBL15498104 | 0.84 | STAT3 (0.51) | STAT3STAT1 | |
| SCHEMBL9866324 | 0.82 | STAT3 (0.49) | STAT3STAT1 | |
| SCHEMBL38329 | 0.82 | STAT3 (0.49) | STAT3STAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240083920-A1 | LOW MOLECULAR WEIGHT CORROLE COMPOSITIONS | TECHNION RESEARCH & DEVELOPMENT FOUNDATION LTD (IL) | 2024-03-14 | — | — | US | disclosed |
| EP-4277906-A1 | LOW MOLECULAR WEIGHT CORROLE COMPOSITIONS | Technion Research & Development Foundation Ltd. (IL) | 2023-11-22 | — | — | EP | disclosed |
| WO-2022153294-A1 | LOW MOLECULAR WEIGHT CORROLE COMPOSITIONS | TECHNION RESEARCH & DEVELOPMENT FOUNDATION LTD (IL) | 2022-07-21 | — | — | WO | disclosed |
| EP-2192899-B1 | TRANSITION METAL COMPLEXES OF CORROLES FOR PREVENTING CARDIOVASCULAR DISEASES OR DISORDERS | TECHNION RES & DEV FOUNDATION (IL) | 2014-10-01 | — | — | EP | disclosed |
| US-8791099-B2 | Transition metal complexes of corroles for preventing cardiovascular diseases or disorders | TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD. (IL) | 2014-07-29 | — | — | US | disclosed |
| US-20140045809-A1 | CORROLES FOR NEUROPROTECTION AND NEURORESCUE | TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD. (IL) | 2014-02-13 | — | — | US | disclosed |
| EP-2244701-B1 | CORROLES FOR NEUROPROTECTION AND NEURORESCUE | TECHNION RES & DEV FOUNDATION (IL) | 2012-05-09 | — | — | EP | disclosed |
| US-20110144078-A1 | TRANSITION METAL COMPLEXES OF CORROLES FOR PREVENTING CARDIOVASCULAR DISEASES OR DISORDERS | TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD. (IL) | 2011-06-16 | — | — | US | disclosed |
| US-20110098262-A1 | CORROLES FOR NEUROPROTECTION AND NEURORESCUE | TECHNION RESEARCH AND DEVELOPEMENT FOUNDATION, LTD. (IL) | 2011-04-28 | — | — | US | disclosed |
| EP-2244701-A2 | CORROLES FOR NEUROPROTECTION AND NEURORESCUE | Technion Research and Development Foundation, Ltd. (IL) | 2010-11-03 | — | — | EP | disclosed |
| EP-2192899-A1 | TRANSITION METAL COMPLEXES OF CORROLES FOR PREVENTING CARDIOVASCULAR DISEASES OR DISORDERS | Technion Research and Development Foundation, Ltd. (IL) | 2010-06-09 | — | — | EP | disclosed |
| WO-2009095923-A2 | CORROLES FOR NEUROPROTECTION AND NEURORESCUE | TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD (IL) | 2009-08-06 | — | — | WO | disclosed |
| WO-2009027965-A1 | TRANSITION METAL COMPLEXES OF CORROLES FOR PREVENTING CARDIOVASCULAR DISEASES OR DISORDERS | TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD. (IL) | 2009-03-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110098262-A1 | CORROLES FOR NEUROPROTECTION AND NEURORESCUE | IAPP, CASP3, SOD1 | STAT3 1610/4885STAT1 2736/4885 |
| US-20140045809-A1 | CORROLES FOR NEUROPROTECTION AND NEURORESCUE | IAPP, CASP3, SOD1 | STAT3 1610/4885STAT1 2736/4885 |
| US-20240083920-A1 | LOW MOLECULAR WEIGHT CORROLE COMPOSITIONS | CA13, CA11, IGFBP3 | STAT3 2579/4885STAT1 4091/4885 |
| US-20110144078-A1 | TRANSITION METAL COMPLEXES OF CORROLES FOR PREVENTING CARDIOVASCULAR DISEASES OR DISORDERS | FABP3, SLC39A14, SLC39A3 | STAT3 1665/4885STAT1 2210/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.